Matches in DBpedia 2014 for { <http://dbpedia.org/resource/C4A> ?p ?o. }
Showing items 1 to 25 of
25
with 100 items per page.
- C4A abstract "Complement C4-A is a protein that in humans is encoded by the C4A gene.This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.".
- C4A entrezgene "720".
- C4A wikiPageID "14987553".
- C4A wikiPageRevisionID "526554907".
- C4A hasPhotoCollection C4A.
- C4A requireManualInspection "no".
- C4A summaryText "This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.".
- C4A updateCitations "yes".
- C4A updatePage "yes".
- C4A updateProteinBox "yes".
- C4A updateSummary "yes".
- C4A subject Category:Blood_antigen_systems.
- C4A subject Category:Complement_system.
- C4A subject Category:Transfusion_medicine.
- C4A type Biomolecule.
- C4A type Protein.
- C4A type BiologicalObject.
- C4A comment "Complement C4-A is a protein that in humans is encoded by the C4A gene.This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components.".
- C4A label "C4A".
- C4A sameAs m.03h3vgh.
- C4A sameAs Q5008198.
- C4A sameAs Q5008198.
- C4A sameAs C4A.
- C4A wasDerivedFrom C4A?oldid=526554907.
- C4A isPrimaryTopicOf C4A.