Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CAMLG> ?p ?o. }
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- CAMLG abstract "Calcium signal-modulating cyclophilin ligand is a protein that in humans is encoded by the CAMLG gene.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.".
- CAMLG entrezgene "819".
- CAMLG wikiPageID "15065729".
- CAMLG wikiPageRevisionID "590849468".
- CAMLG hasPhotoCollection CAMLG.
- CAMLG requireManualInspection "no".
- CAMLG summaryText "The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.".
- CAMLG updateCitations "yes".
- CAMLG updatePage "yes".
- CAMLG updateProteinBox "yes".
- CAMLG updateSummary "yes".
- CAMLG type Biomolecule.
- CAMLG type Protein.
- CAMLG type BiologicalObject.
- CAMLG comment "Calcium signal-modulating cyclophilin ligand is a protein that in humans is encoded by the CAMLG gene.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin.".
- CAMLG label "CAMLG".
- CAMLG sameAs m.03hgby7.
- CAMLG sameAs Q5008661.
- CAMLG sameAs Q5008661.
- CAMLG sameAs 421.
- CAMLG wasDerivedFrom CAMLG?oldid=590849468.
- CAMLG isPrimaryTopicOf CAMLG.