Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CD11a> ?p ?o. }
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- CD11a abstract "Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.CD11a is one of the two components, along with CD18, which form lymphocyte function-associated antigen-1.Efalizumab acts as an immunosuppressant by binding to CD11a.".
- CD11a entrezgene "3683".
- CD11a wikiPageExternalLink report.cgi?report=orth_overview&gene_id=3683.
- CD11a wikiPageExternalLink index.shtml.
- CD11a wikiPageID "5874177".
- CD11a wikiPageRevisionID "603075032".
- CD11a hasPhotoCollection CD11a.
- CD11a requireManualInspection "no".
- CD11a summaryText "ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain to form the integrin lymphocyte function-associated antigen-1 , which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 , and also functions in lymphocyte costimulatory signaling.".
- CD11a updateCitations "yes".
- CD11a updatePage "yes".
- CD11a updateProteinBox "yes".
- CD11a updateSummary "yes".
- CD11a subject Category:Integrins.
- CD11a type Biomolecule.
- CD11a type Protein.
- CD11a type BiologicalObject.
- CD11a comment "Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.".
- CD11a label "CD11".
- CD11a label "CD11a".
- CD11a label "CD11a".
- CD11a label "Интегрин альфа-L".
- CD11a sameAs CD11.
- CD11a sameAs CD11a.
- CD11a sameAs ITGAL.
- CD11a sameAs m.0fb6cd.
- CD11a sameAs Q3648604.
- CD11a sameAs Q3648604.
- CD11a sameAs 572.
- CD11a wasDerivedFrom CD11a?oldid=603075032.
- CD11a isPrimaryTopicOf CD11a.