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- CD20-like_family abstract "In molecular biology, the CD20-like family of proteins includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc, MS4A2. MS4A2 has a tetrameric structure consisting of a single IgE-binding alpha subunit, a single beta subunit, and two disulfide-linked gamma subunits. It has four putative transmembrane segments and a probable topology where both amino- and carboxy termini protrude into the cytoplasm. This family also includes LR8 like proteins from humans (TMEM176B), mice and rats. The function of the human LR8 protein is unknown although it is known to be strongly expressed in the lung fibroblasts. This family also includes sarcospan, a transmembrane component of dystrophin-associated glycoprotein. Loss of the sarcoglycan complex and sarcospan alone is sufficient to cause muscular dystrophy. The role of the sarcoglycan complex and sarcospan is thought to be to strengthen the dystrophin axis connecting the basement membrane with the cytoskeleton.".
- CD20-like_family symbol "CD20".
- CD20-like_family thumbnail PDB_2osl_EBI.jpg?width=300.
- CD20-like_family wikiPageID "32239282".
- CD20-like_family wikiPageRevisionID "590872606".
- CD20-like_family caption "crystal structure of rituximab fab in complex with an epitope peptide".
- CD20-like_family hasPhotoCollection CD20-like_family.
- CD20-like_family interpro "IPR007237".
- CD20-like_family name "CD20-like family".
- CD20-like_family pfam "PF04103".
- CD20-like_family pfamClan "CL0347".
- CD20-like_family symbol "CD20".
- CD20-like_family tcdb "1".
- CD20-like_family subject Category:Protein_families.
- CD20-like_family type Biomolecule.
- CD20-like_family type Protein.
- CD20-like_family type BiologicalObject.
- CD20-like_family comment "In molecular biology, the CD20-like family of proteins includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc, MS4A2. MS4A2 has a tetrameric structure consisting of a single IgE-binding alpha subunit, a single beta subunit, and two disulfide-linked gamma subunits. It has four putative transmembrane segments and a probable topology where both amino- and carboxy termini protrude into the cytoplasm.".
- CD20-like_family label "CD20-like family".
- CD20-like_family sameAs m.0gx_h0g.
- CD20-like_family sameAs Q5009793.
- CD20-like_family sameAs Q5009793.
- CD20-like_family wasDerivedFrom CD20-like_family?oldid=590872606.
- CD20-like_family depiction PDB_2osl_EBI.jpg.
- CD20-like_family isPrimaryTopicOf CD20-like_family.
