Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CDC20> ?p ?o. }
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- CDC20 abstract "The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APCCdc20 protein complex has two main downstream targets. Firstly, it targets securin for destruction, enabling the eventual destruction of cohesin and thus sister chromatid separation. It also targets S and M-phase (S/M) cyclins for destruction, which inactivates S/M cyclin-dependent kinases (Cdks) and allows the cell to exit from mitosis. A closely related protein, Cdc20homologue-1 (Cdh1) plays a complementary role in the cell cycle.CDC20 appears to act as a regulatory protein interacting with many other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes: nuclear movement prior to anaphase, and chromosome separation.".
- CDC20 entrezgene "991".
- CDC20 thumbnail APC_Subunits.jpg?width=300.
- CDC20 wikiPageID "14138381".
- CDC20 wikiPageRevisionID "603075390".
- CDC20 hasPhotoCollection CDC20.
- CDC20 requireManualInspection "no".
- CDC20 updateCitations "yes".
- CDC20 updatePage "yes".
- CDC20 updateProteinBox "yes".
- CDC20 updateSummary "no".
- CDC20 type Biomolecule.
- CDC20 type Protein.
- CDC20 type BiologicalObject.
- CDC20 comment "The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APCCdc20 protein complex has two main downstream targets.".
- CDC20 label "CDC20".
- CDC20 sameAs m.03cvrkx.
- CDC20 sameAs Q5009871.
- CDC20 sameAs Q5009871.
- CDC20 wasDerivedFrom CDC20?oldid=603075390.
- CDC20 depiction APC_Subunits.jpg.
- CDC20 isPrimaryTopicOf CDC20.
