Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CLCA2> ?p ?o. }
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- CLCA2 abstract "Calcium-activated chloride channel regulator 2 is a protein that in humans is encoded by the CLCA2 gene.The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. Protein structure prediction methods suggest the N-terminal region of CLCA2 protein is a zinc metalloprotease.".
- CLCA2 entrezgene "9635".
- CLCA2 wikiPageID "14876282".
- CLCA2 wikiPageRevisionID "580117983".
- CLCA2 hasPhotoCollection CLCA2.
- CLCA2 requireManualInspection "no".
- CLCA2 summaryText "The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. Protein structure prediction methods suggest the N-terminal region of CLCA2 protein is a zinc metalloprotease.".
- CLCA2 updateCitations "yes".
- CLCA2 updatePage "yes".
- CLCA2 updateProteinBox "yes".
- CLCA2 updateSummary "yes".
- CLCA2 subject Category:Ion_channels.
- CLCA2 type Biomolecule.
- CLCA2 type Protein.
- CLCA2 type BiologicalObject.
- CLCA2 comment "Calcium-activated chloride channel regulator 2 is a protein that in humans is encoded by the CLCA2 gene.The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions.".
- CLCA2 label "CLCA2".
- CLCA2 sameAs m.03g_xcw.
- CLCA2 sameAs Q5012684.
- CLCA2 sameAs Q5012684.
- CLCA2 wasDerivedFrom CLCA2?oldid=580117983.
- CLCA2 isPrimaryTopicOf CLCA2.