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- CLEC4M abstract "C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299 (cluster of differentiation 299).This gene encodes L-SIGN (liver/lymph node-specific intracellular adhesion molecules-3 grabbing non-integrin), a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.".
- CLEC4M entrezgene "10332".
- CLEC4M wikiPageID "14179243".
- CLEC4M wikiPageRevisionID "593788809".
- CLEC4M hasPhotoCollection CLEC4M.
- CLEC4M requireManualInspection "no".
- CLEC4M summaryText "This gene encodes L-SIGN , a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.".
- CLEC4M updateCitations "yes".
- CLEC4M updatePage "yes".
- CLEC4M updateProteinBox "yes".
- CLEC4M updateSummary "yes".
- CLEC4M subject Category:Clusters_of_differentiation.
- CLEC4M type Biomolecule.
- CLEC4M type Protein.
- CLEC4M type BiologicalObject.
- CLEC4M comment "C-type lectin domain family 4 member M is a protein that in humans is encoded by the CLEC4M gene. CLEC4M has also been designated as CD299 (cluster of differentiation 299).This gene encodes L-SIGN (liver/lymph node-specific intracellular adhesion molecules-3 grabbing non-integrin), a type II integral membrane protein that is 77% identical to CD209 antigen, an HIV gp120-binding protein.".
- CLEC4M label "CLEC4M".
- CLEC4M sameAs m.03cx16p.
- CLEC4M sameAs Q5012732.
- CLEC4M sameAs Q5012732.
- CLEC4M wasDerivedFrom CLEC4M?oldid=593788809.
- CLEC4M isPrimaryTopicOf CLEC4M.