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- CLEC7A abstract "C-type lectin domain family 7 member A/Dectin is a protein that in humans is encoded by the CLEC7A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is found on myeloid Dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.".
- CLEC7A entrezgene "64581".
- CLEC7A wikiPageExternalLink nature377_3.pdf.
- CLEC7A wikiPageID "14765246".
- CLEC7A wikiPageRevisionID "588572385".
- CLEC7A hasPhotoCollection CLEC7A.
- CLEC7A requireManualInspection "no".
- CLEC7A summaryText "This gene encodes a member of the C-type lectin/C-type lectin-like domain superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is found on myeloid Dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.".
- CLEC7A updateCitations "yes".
- CLEC7A updatePage "yes".
- CLEC7A updateProteinBox "yes".
- CLEC7A updateSummary "yes".
- CLEC7A subject Category:C-type_lectins.
- CLEC7A type Biomolecule.
- CLEC7A type Protein.
- CLEC7A type BiologicalObject.
- CLEC7A comment "C-type lectin domain family 7 member A/Dectin is a protein that in humans is encoded by the CLEC7A gene.This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif.".
- CLEC7A label "CLEC7A".
- CLEC7A sameAs CLEC7A.
- CLEC7A sameAs m.03gx78z.
- CLEC7A sameAs Q5012735.
- CLEC7A sameAs Q5012735.
- CLEC7A wasDerivedFrom CLEC7A?oldid=588572385.
- CLEC7A isPrimaryTopicOf CLEC7A.