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- CPSF1 abstract "Cleavage and polyadenylation specificity factor subunit 1 is a protein that in humans is encoded by the CPSF1 gene.In most cases eukaryotic pre-messenger(m)RNA 3 prime ends are processed in two coordinated steps. First there is a site-specific cleavage by an endonuclease and then the addition of a poly(A) tail at the 3 prime end of the 5 prime cleavage product. Cleavage requires four multisubunit complexes, namely cleavage and polyadenylation specificity factor (CPSF), cleavage stimulation factor (CstF), cleavage factors Im and IIm (CFIm and CFIIm), along with a single subunit poly(A)polymerase (PAP). CPSF1 is the largest component of the CPSF complex composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1, and located in the nucleus. CPSF1 recognizes the AAUAAA sequence leading to addition of poly(A) to the 3-prime end of the mRNA.".
- CPSF1 entrezgene "29894".
- CPSF1 wikiPageID "14799048".
- CPSF1 wikiPageRevisionID "593867826".
- CPSF1 hasPhotoCollection CPSF1.
- CPSF1 requireManualInspection "no".
- CPSF1 updateCitations "yes".
- CPSF1 updatePage "yes".
- CPSF1 updateProteinBox "yes".
- CPSF1 updateSummary "yes".
- CPSF1 type Biomolecule.
- CPSF1 type Protein.
- CPSF1 type BiologicalObject.
- CPSF1 comment "Cleavage and polyadenylation specificity factor subunit 1 is a protein that in humans is encoded by the CPSF1 gene.In most cases eukaryotic pre-messenger(m)RNA 3 prime ends are processed in two coordinated steps. First there is a site-specific cleavage by an endonuclease and then the addition of a poly(A) tail at the 3 prime end of the 5 prime cleavage product.".
- CPSF1 label "CPSF1".
- CPSF1 sameAs m.03gycm9.
- CPSF1 sameAs Q5013723.
- CPSF1 sameAs Q5013723.
- CPSF1 wasDerivedFrom CPSF1?oldid=593867826.
- CPSF1 isPrimaryTopicOf CPSF1.