Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CTEP> ?p ?o. }
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- CTEP abstract "CTEP is a research drug developed by Hoffmann-La Roche that acts as a selective allosteric antagonist of the metabotropic glutamate receptor subtype mGluR5, binding with nanomolar affinity and over 1000x selectivity over all other receptor targets tested. In animal studies it was found to have a high oral bioavailability and a long duration of action, lasting 18 hours after a single dose, giving it considerably improved properties over older mGluR5 antagonists such as MPEP and fenobam.".
- CTEP iupacName "2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine".
- CTEP pubchem "11646823".
- CTEP thumbnail CTEP_structure.png?width=300.
- CTEP wikiPageID "34541581".
- CTEP wikiPageRevisionID "560778835".
- CTEP c "19".
- CTEP chemspiderid "9821562".
- CTEP cl "1".
- CTEP f "3".
- CTEP h "13".
- CTEP hasPhotoCollection CTEP.
- CTEP inchi "1".
- CTEP inchikey "GOHCTCOGYKAJLZ-UHFFFAOYAI".
- CTEP iupacName "2".
- CTEP molecularWeight "391.774".
- CTEP n "3".
- CTEP o "1".
- CTEP pubchem "11646823".
- CTEP smiles "Clc2ccC#Cc1ncn-cccc3OCF".
- CTEP smiles "FCOc3ccccc3".
- CTEP stdinchi "1".
- CTEP stdinchikey "GOHCTCOGYKAJLZ-UHFFFAOYSA-N".
- CTEP width "220".
- CTEP subject Category:Alkynes.
- CTEP subject Category:Imidazoles.
- CTEP subject Category:Pyridines.
- CTEP subject Category:Receptor_antagonists.
- CTEP type Abstraction100002137.
- CTEP type Acetylene114600742.
- CTEP type AliphaticCompound114601294.
- CTEP type Alkynes.
- CTEP type Base114618253.
- CTEP type Chemical114806838.
- CTEP type Compound114818238.
- CTEP type Imidazole114916670.
- CTEP type Imidazoles.
- CTEP type Material114580897.
- CTEP type Matter100020827.
- CTEP type OrganicCompound114727670.
- CTEP type Part113809207.
- CTEP type PhysicalEntity100001930.
- CTEP type Pyridine114692510.
- CTEP type Pyridines.
- CTEP type Relation100031921.
- CTEP type Substance100019613.
- CTEP type Drug.
- CTEP type FunctionalSubstance.
- CTEP comment "CTEP is a research drug developed by Hoffmann-La Roche that acts as a selective allosteric antagonist of the metabotropic glutamate receptor subtype mGluR5, binding with nanomolar affinity and over 1000x selectivity over all other receptor targets tested. In animal studies it was found to have a high oral bioavailability and a long duration of action, lasting 18 hours after a single dose, giving it considerably improved properties over older mGluR5 antagonists such as MPEP and fenobam.".
- CTEP label "CTEP".
- CTEP sameAs m.0j240xf.
- CTEP sameAs Q5014559.
- CTEP sameAs Q5014559.
- CTEP sameAs CTEP.
- CTEP wasDerivedFrom CTEP?oldid=560778835.
- CTEP depiction CTEP_structure.png.
- CTEP isPrimaryTopicOf CTEP.
