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- CXCL14 abstract "Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine). Mature CXCL14 has many of the conserved features of the CXC chemokine subfamily but has some differences too, such as a shorter N-terminus and five extra amino acids in the region between its third and fourth cysteines. CXCL14 is constitutively expressed at high levels in many normal tissues, where its cellular source is thought to be fibroblasts.However, it is reduced or absent from most cancer cells. This chemokine is chemotactic for monocytes and can activate these cells in the presence of an inflammatory mediator called prostaglandin-E2 (PGE2). It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis. The gene for CXCL14 contains four exons and is located on chromosome 5 in humans.".
- CXCL14 arm "q".
- CXCL14 band "31".
- CXCL14 chromosome "5".
- CXCL14 entrezgene "9547".
- CXCL14 hgncid "10640".
- CXCL14 omim "604186".
- CXCL14 pdb "2HDL".
- CXCL14 refseq "NM_004887".
- CXCL14 symbol "CXCL14".
- CXCL14 symbol "SCYB14, BRAK, NJAC, bolekine, Kec, MIP-2g, BMAC, KS1".
- CXCL14 uniprot "O95715".
- CXCL14 wikiPageID "8877946".
- CXCL14 wikiPageRevisionID "544648448".
- CXCL14 altsymbols "SCYB14, BRAK, NJAC, bolekine, Kec, MIP-2g, BMAC, KS1".
- CXCL14 arm "q".
- CXCL14 band "31".
- CXCL14 chromosome "5".
- CXCL14 entrezgene "9547".
- CXCL14 hasPhotoCollection CXCL14.
- CXCL14 hgncid "10640".
- CXCL14 name "chemokine ligand 14".
- CXCL14 omim "604186".
- CXCL14 pdb "2".
- CXCL14 refseq "NM_004887".
- CXCL14 symbol "CXCL14".
- CXCL14 uniprot "O95715".
- CXCL14 subject Category:Cytokines.
- CXCL14 type Biomolecule.
- CXCL14 type Protein.
- CXCL14 type ProteinMolecule.
- CXCL14 type BiologicalObject.
- CXCL14 comment "Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine). Mature CXCL14 has many of the conserved features of the CXC chemokine subfamily but has some differences too, such as a shorter N-terminus and five extra amino acids in the region between its third and fourth cysteines.".
- CXCL14 label "CXCL14".
- CXCL14 sameAs m.027n00p.
- CXCL14 sameAs Q5014878.
- CXCL14 sameAs Q5014878.
- CXCL14 wasDerivedFrom CXCL14?oldid=544648448.
- CXCL14 isPrimaryTopicOf CXCL14.
- CXCL14 name "chemokine (C-X-C motif) ligand 14".