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- Capping_enzyme abstract "A capping enzyme is an enzyme that catalyzes the attachment of the 5' cap to messenger RNA molecules that are in the process of being synthesized in the cell nucleus during the first stages of gene expression. The addition of the cap occurs co-transcriptionally, after the growing RNA molecule contains as little as 25 nucleotides. The enzyme can only catalyze its reaction when bound to the phosphorylated carboxyl-terminal domain of RNA polymerase II; therefore it is specific to RNAs synthesized by this polymerase rather than those synthesized by RNA polymerase I or RNA polymerase III. Pre-mRNA undergoes a series of modifications - 5' capping, splicing and 3' polyadenylation before becoming mature mRNA that exits the nucleus to be translated into functional proteins and capping of the 5' end is the first of these modifications. Collectively, the enzymes, RNA triphosphatase, guanylyltransferase, and methyltransferase that are involved in the addition of the 5' cap to the mRNA are called "capping enzymes."".
- Capping_enzyme ecNumber "2.7.7.50".
- Capping_enzyme thumbnail PDB_1ckm_EBI.jpg?width=300.
- Capping_enzyme wikiPageID "6924749".
- Capping_enzyme wikiPageRevisionID "606268886".
- Capping_enzyme casNumber "56941".
- Capping_enzyme ecNumber "2.7".
- Capping_enzyme hasPhotoCollection Capping_enzyme.
- Capping_enzyme name "mRNA guanylyltransferase".
- Capping_enzyme subject Category:Gene_expression.
- Capping_enzyme type Biomolecule.
- Capping_enzyme type Enzyme.
- Capping_enzyme type BiologicalObject.
- Capping_enzyme comment "A capping enzyme is an enzyme that catalyzes the attachment of the 5' cap to messenger RNA molecules that are in the process of being synthesized in the cell nucleus during the first stages of gene expression. The addition of the cap occurs co-transcriptionally, after the growing RNA molecule contains as little as 25 nucleotides.".
- Capping_enzyme label "Capping enzyme".
- Capping_enzyme label "MRNA-Capping-Enzym".
- Capping_enzyme sameAs MRNA-Capping-Enzym.
- Capping_enzyme sameAs m.0gx8v4.
- Capping_enzyme sameAs Q1881795.
- Capping_enzyme sameAs Q1881795.
- Capping_enzyme wasDerivedFrom Capping_enzyme?oldid=606268886.
- Capping_enzyme depiction PDB_1ckm_EBI.jpg.
- Capping_enzyme isPrimaryTopicOf Capping_enzyme.
- Capping_enzyme name "mRNA guanylyltransferase".
