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- Carisbamate abstract "Carisbamate (YKP 509, proposed trade name Comfyde) is an experimental anticonvulsant drug under development by Johnson & Johnson Pharmaceutical Research and Development. In 1998, the compound was in-licensed from SK Corp. (currently Life Science Business Division of SK Holdings), a South Korean company. A phase II clinical trial in the treatment of partial seizures demonstrated that the compound has efficacy in the treatment of partial seizures and a good safety profile. Since late 2006, the compound has been undergoing a large multicenter phase III clinical trial for the treatment of partial seizures. Its mechanism of action is unknown.On October 24, 2008, Johnson & Johnson announced that it had submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) for carisbamate. Carisbamate has received provisional approval by the FDA to be marketed under the brand name of Comfyde. However, on August 21, 2009, Johnson & Johnson reported that the FDA had failed to give marketing approval.A double-blind, placebo-controlled trial cf carisbamate in 323 patients with migraine failed to demonstrate that the active drug was more effective than placebo. However, carisbamate was well tolerated at doses up to 600 mg/day.".
- Carisbamate atcPrefix "N03".
- Carisbamate atcSuffix "AX19".
- Carisbamate casNumber "194085-75-1".
- Carisbamate fdaUniiCode "P7725I9V3Z".
- Carisbamate iupacName "(S)-2-O-carbamoyl-1-o-chlorophenyl-ethanol".
- Carisbamate pubchem "9942577".
- Carisbamate thumbnail Carisbamate.png?width=300.
- Carisbamate wikiPageID "10600394".
- Carisbamate wikiPageRevisionID "447761334".
- Carisbamate atcPrefix "N03".
- Carisbamate atcSuffix "AX19".
- Carisbamate c "9".
- Carisbamate casNumber "194085".
- Carisbamate chemspiderid "8118189".
- Carisbamate cl "1".
- Carisbamate h "10".
- Carisbamate hasPhotoCollection Carisbamate.
- Carisbamate inchi "1".
- Carisbamate inchikey "OLBWFRRUHYQABZ-QMMMGPOBBO".
- Carisbamate iupacName "-2".
- Carisbamate molecularWeight "215.633".
- Carisbamate n "1".
- Carisbamate o "3".
- Carisbamate pubchem "9942577".
- Carisbamate smiles "Clc1ccccc1[C@@H]COCN".
- Carisbamate stdinchi "1".
- Carisbamate stdinchikey "OLBWFRRUHYQABZ-QMMMGPOBSA-N".
- Carisbamate unii "P7725I9V3Z".
- Carisbamate verifiedrevid "444292166".
- Carisbamate subject Category:Alcohols.
- Carisbamate subject Category:Anticonvulsants.
- Carisbamate subject Category:Carbamates.
- Carisbamate subject Category:Johnson_&_Johnson.
- Carisbamate subject Category:Organochlorides.
- Carisbamate type Abstraction100002137.
- Carisbamate type Agent114778436.
- Carisbamate type Alcohol107884567.
- Carisbamate type Alcohols.
- Carisbamate type Beverage107881800.
- Carisbamate type Carbamate114792281.
- Carisbamate type Carbamates.
- Carisbamate type CausalAgent100007347.
- Carisbamate type Chemical114806838.
- Carisbamate type Compound114818238.
- Carisbamate type Drug103247620.
- Carisbamate type DrugOfAbuse103248958.
- Carisbamate type Fluid114939900.
- Carisbamate type Food100021265.
- Carisbamate type Liquid114940386.
- Carisbamate type Material114580897.
- Carisbamate type Matter100020827.
- Carisbamate type Part113809207.
- Carisbamate type PhysicalEntity100001930.
- Carisbamate type Relation100031921.
- Carisbamate type Salt115010703.
- Carisbamate type Substance100019613.
- Carisbamate type Substance100020090.
- Carisbamate type Drug.
- Carisbamate type DrugProduct.
- Carisbamate type FunctionalSubstance.
- Carisbamate comment "Carisbamate (YKP 509, proposed trade name Comfyde) is an experimental anticonvulsant drug under development by Johnson & Johnson Pharmaceutical Research and Development. In 1998, the compound was in-licensed from SK Corp. (currently Life Science Business Division of SK Holdings), a South Korean company. A phase II clinical trial in the treatment of partial seizures demonstrated that the compound has efficacy in the treatment of partial seizures and a good safety profile.".
- Carisbamate label "Carisbamate".
- Carisbamate sameAs m.02qjwj3.
- Carisbamate sameAs Q5039678.
- Carisbamate sameAs Q5039678.
- Carisbamate sameAs Carisbamate.
- Carisbamate wasDerivedFrom Carisbamate?oldid=447761334.
- Carisbamate depiction Carisbamate.png.
- Carisbamate isPrimaryTopicOf Carisbamate.