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- Caspase_10 abstract "Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.".
- Caspase_10 entrezgene "843".
- Caspase_10 wikiPageExternalLink merops.cgi?id=C14.011.
- Caspase_10 wikiPageExternalLink br.fcgi?book=gene&part=alps.
- Caspase_10 wikiPageID "14144021".
- Caspase_10 wikiPageRevisionID "603065593".
- Caspase_10 hasPhotoCollection Caspase_10.
- Caspase_10 requireManualInspection "no".
- Caspase_10 summaryText "This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.".
- Caspase_10 updateCitations "yes".
- Caspase_10 updatePage "yes".
- Caspase_10 updateProteinBox "yes".
- Caspase_10 updateSummary "yes".
- Caspase_10 type Biomolecule.
- Caspase_10 type Protein.
- Caspase_10 type BiologicalObject.
- Caspase_10 comment "Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.".
- Caspase_10 label "Caspase 10".
- Caspase_10 sameAs m.03cvz0j.
- Caspase_10 sameAs Q5049048.
- Caspase_10 sameAs Q5049048.
- Caspase_10 sameAs CASP10.
- Caspase_10 wasDerivedFrom Caspase_10?oldid=603065593.
- Caspase_10 isPrimaryTopicOf Caspase_10.