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- Caspase_14 abstract "Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene.The CASP14 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.".
- Caspase_14 entrezgene "23581".
- Caspase_14 wikiPageExternalLink merops.cgi?id=C14.018.
- Caspase_14 wikiPageID "14794876".
- Caspase_14 wikiPageRevisionID "590864868".
- Caspase_14 hasPhotoCollection Caspase_14.
- Caspase_14 requireManualInspection "no".
- Caspase_14 summaryText "The CASP14 gene encodes a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.".
- Caspase_14 updateCitations "yes".
- Caspase_14 updatePage "yes".
- Caspase_14 updateProteinBox "yes".
- Caspase_14 updateSummary "yes".
- Caspase_14 type Biomolecule.
- Caspase_14 type Protein.
- Caspase_14 type BiologicalObject.
- Caspase_14 comment "Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene.The CASP14 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.".
- Caspase_14 label "Caspase 14".
- Caspase_14 sameAs m.03gy55d.
- Caspase_14 sameAs Q5049050.
- Caspase_14 sameAs Q5049050.
- Caspase_14 wasDerivedFrom Caspase_14?oldid=590864868.
- Caspase_14 isPrimaryTopicOf Caspase_14.