Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Caspase_8> ?p ?o. }
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- Caspase_8 abstract "Caspase 8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase 3.CASP8 orthologs have been identified in numerous mammals for which complete genome data are available. These unique orthologs are also present in birds.".
- Caspase_8 entrezgene "841".
- Caspase_8 wikiPageExternalLink search_protein_id.php?id=casp8.
- Caspase_8 wikiPageExternalLink merops.cgi?id=C14.009.
- Caspase_8 wikiPageExternalLink watch?v=29AMumxsEo0.
- Caspase_8 wikiPageID "10030080".
- Caspase_8 wikiPageRevisionID "603065634".
- Caspase_8 hasPhotoCollection Caspase_8.
- Caspase_8 requireManualInspection "no".
- Caspase_8 summaryText "The CASP8 gene encodes a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.".
- Caspase_8 updateCitations "yes".
- Caspase_8 updatePage "yes".
- Caspase_8 updateProteinBox "yes".
- Caspase_8 updateSummary "yes".
- Caspase_8 subject Category:Peptidase.
- Caspase_8 type Biomolecule.
- Caspase_8 type Protein.
- Caspase_8 type BiologicalObject.
- Caspase_8 comment "Caspase 8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase 3.CASP8 orthologs have been identified in numerous mammals for which complete genome data are available. These unique orthologs are also present in birds.".
- Caspase_8 label "Caspase 8".
- Caspase_8 sameAs CASP8.
- Caspase_8 sameAs m.02p_bzl.
- Caspase_8 sameAs Q5049059.
- Caspase_8 sameAs Q5049059.
- Caspase_8 sameAs CASP8.
- Caspase_8 wasDerivedFrom Caspase_8?oldid=603065634.
- Caspase_8 isPrimaryTopicOf Caspase_8.