Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Cathepsin_F> ?p ?o. }
Showing items 1 to 24 of
24
with 100 items per page.
- Cathepsin_F abstract "Cathepsin F is a protein that in humans is encoded by the CTSF gene.Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. In general, cathepsins contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251-amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids that contains a 19-residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.".
- Cathepsin_F entrezgene "8722".
- Cathepsin_F wikiPageExternalLink merops.cgi?id=C01.018.
- Cathepsin_F wikiPageID "15066289".
- Cathepsin_F wikiPageRevisionID "590868090".
- Cathepsin_F hasPhotoCollection Cathepsin_F.
- Cathepsin_F requireManualInspection "no".
- Cathepsin_F summaryText "Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. In general, cathepsins contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids that contains a 19-residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.".
- Cathepsin_F updateCitations "yes".
- Cathepsin_F updatePage "yes".
- Cathepsin_F updateProteinBox "yes".
- Cathepsin_F updateSummary "yes".
- Cathepsin_F subject Category:Peptidase.
- Cathepsin_F type Biomolecule.
- Cathepsin_F type Protein.
- Cathepsin_F type BiologicalObject.
- Cathepsin_F comment "Cathepsin F is a protein that in humans is encoded by the CTSF gene.Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. In general, cathepsins contain a signal sequence, followed by a propeptide and then a catalytically active mature region.".
- Cathepsin_F label "Cathepsin F".
- Cathepsin_F sameAs m.03hgcts.
- Cathepsin_F sameAs Q5052482.
- Cathepsin_F sameAs Q5052482.
- Cathepsin_F sameAs 2735.
- Cathepsin_F wasDerivedFrom Cathepsin_F?oldid=590868090.
- Cathepsin_F isPrimaryTopicOf Cathepsin_F.