Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Cell-penetrating_peptide> ?p ?o. }
Showing items 1 to 37 of
37
with 100 items per page.
- Cell-penetrating_peptide abstract "Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The "cargo" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (Tat) from Human Immunodeficiency Virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.".
- Cell-penetrating_peptide thumbnail Direct_penetrating_example.png?width=300.
- Cell-penetrating_peptide wikiPageExternalLink cellppd.
- Cell-penetrating_peptide wikiPageExternalLink cppsite.
- Cell-penetrating_peptide wikiPageExternalLink bas015.abstract.
- Cell-penetrating_peptide wikiPageExternalLink www.cell-penetrating-peptides.com.
- Cell-penetrating_peptide wikiPageExternalLink crossing.asp.
- Cell-penetrating_peptide wikiPageExternalLink abstract.
- Cell-penetrating_peptide wikiPageID "9470331".
- Cell-penetrating_peptide wikiPageRevisionID "594272431".
- Cell-penetrating_peptide hasPhotoCollection Cell-penetrating_peptide.
- Cell-penetrating_peptide subject Category:Cell_biology.
- Cell-penetrating_peptide subject Category:Peptides.
- Cell-penetrating_peptide type Abstraction100002137.
- Cell-penetrating_peptide type Amide114724264.
- Cell-penetrating_peptide type Chemical114806838.
- Cell-penetrating_peptide type Compound114818238.
- Cell-penetrating_peptide type Material114580897.
- Cell-penetrating_peptide type Matter100020827.
- Cell-penetrating_peptide type OrganicCompound114727670.
- Cell-penetrating_peptide type Part113809207.
- Cell-penetrating_peptide type Peptide114743046.
- Cell-penetrating_peptide type Peptides.
- Cell-penetrating_peptide type PhysicalEntity100001930.
- Cell-penetrating_peptide type Relation100031921.
- Cell-penetrating_peptide type Substance100019613.
- Cell-penetrating_peptide comment "Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The "cargo" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions.".
- Cell-penetrating_peptide label "Cell-penetrating peptide".
- Cell-penetrating_peptide label "Zellpenetrierendes Peptid".
- Cell-penetrating_peptide sameAs Zellpenetrierendes_Peptid.
- Cell-penetrating_peptide sameAs m.028b5cw.
- Cell-penetrating_peptide sameAs Q189096.
- Cell-penetrating_peptide sameAs Q189096.
- Cell-penetrating_peptide sameAs Cell-penetrating_peptide.
- Cell-penetrating_peptide wasDerivedFrom Cell-penetrating_peptide?oldid=594272431.
- Cell-penetrating_peptide depiction Direct_penetrating_example.png.
- Cell-penetrating_peptide isPrimaryTopicOf Cell-penetrating_peptide.
