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- ChIP-on-chip abstract "ChIP-on-chip (also known as ChIP-chip) is a technique that combines chromatin immunoprecipitation ("ChIP") with microarray technology ("chip"). Like regular ChIP, ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo. Specifically, it allows the identification of the cistrome, sum of binding sites, for DNA-binding proteins on a genome-wide basis. Whole-genome analysis can be performed to determine the locations of binding sites for almost any protein of interest. As the name of the technique suggests, such proteins are generally those operating in the context of chromatin. The most prominent representatives of this class are transcription factors, replication-related proteins, like ORC, histones, their variants, and histone modifications.The goal of ChIP-on-chip is to locate protein binding sites that may help identify functional elements in the genome. For example, in the case of a transcription factor as a protein of interest, one can determine its transcription factor binding sites throughout the genome. Other proteins allow the identification of promoter regions, enhancers, repressors and silencing elements, insulators, boundary elements, and sequences that control DNA replication. If histones are subject of interest, it is believed that the distribution of modifications and their localizations may offer new insights into the mechanisms of regulation.One of the long-term goals ChIP-on-chip was designed for is to establish a catalogue of (selected) organisms that lists all protein-DNA interactions under various physiological conditions. This knowledge would ultimately help in the understanding of the machinery behind gene regulation, cell proliferation, and disease progression. Hence, ChIP-on-chip offers not only huge potential to complement our knowledge about the orchestration of the genome on the nucleotide level, but also on higher levels of information and regulation as it is propagated by research on epigenetics.".
- ChIP-on-chip thumbnail ChIP-on-chip_workflow_overview.svg?width=300.
- ChIP-on-chip wikiPageExternalLink btp075.
- ChIP-on-chip wikiPageExternalLink tamalpais.cgi.
- ChIP-on-chip wikiPageExternalLink chip-on-chip.
- ChIP-on-chip wikiPageExternalLink ChIP-chip.
- ChIP-on-chip wikiPageExternalLink rMAT.html.
- ChIP-on-chip wikiPageExternalLink www.chiponchip.net.
- ChIP-on-chip wikiPageExternalLink www.chiponchip.org.
- ChIP-on-chip wikiPageExternalLink index.html.
- ChIP-on-chip wikiPageExternalLink 10005107.
- ChIP-on-chip wikiPageExternalLink 12457.abstract.
- ChIP-on-chip wikiPageID "9756354".
- ChIP-on-chip wikiPageRevisionID "602706773".
- ChIP-on-chip hasPhotoCollection ChIP-on-chip.
- ChIP-on-chip subject Category:Bioinformatics.
- ChIP-on-chip subject Category:Microarrays.
- ChIP-on-chip subject Category:Molecular_biology.
- ChIP-on-chip subject Category:Molecular_biology_techniques.
- ChIP-on-chip subject Category:Protein_methods.
- ChIP-on-chip type Ability105616246.
- ChIP-on-chip type Abstraction100002137.
- ChIP-on-chip type Cognition100023271.
- ChIP-on-chip type Know-how105616786.
- ChIP-on-chip type Method105660268.
- ChIP-on-chip type MolecularBiologyTechniques.
- ChIP-on-chip type ProteinMethods.
- ChIP-on-chip type PsychologicalFeature100023100.
- ChIP-on-chip type Technique105665146.
- ChIP-on-chip comment "ChIP-on-chip (also known as ChIP-chip) is a technique that combines chromatin immunoprecipitation ("ChIP") with microarray technology ("chip"). Like regular ChIP, ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo. Specifically, it allows the identification of the cistrome, sum of binding sites, for DNA-binding proteins on a genome-wide basis. Whole-genome analysis can be performed to determine the locations of binding sites for almost any protein of interest.".
- ChIP-on-chip label "ChIP-on-Chip".
- ChIP-on-chip label "ChIP-on-chip".
- ChIP-on-chip label "ChIP-on-chip".
- ChIP-on-chip label "Chip on chip".
- ChIP-on-chip sameAs ChIP-on-Chip.
- ChIP-on-chip sameAs Chip_on_chip.
- ChIP-on-chip sameAs ChIP-on-chip.
- ChIP-on-chip sameAs m.02pr6y5.
- ChIP-on-chip sameAs Q7815764.
- ChIP-on-chip sameAs Q7815764.
- ChIP-on-chip sameAs ChIP-on-chip.
- ChIP-on-chip wasDerivedFrom ChIP-on-chip?oldid=602706773.
- ChIP-on-chip depiction ChIP-on-chip_workflow_overview.svg.
- ChIP-on-chip isPrimaryTopicOf ChIP-on-chip.
