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- Chemical_compound_microarray abstract "A chemical compound microarray is a collection of organic chemical compounds spotted on a solid surface, such as glass and plastic. This microarray format is very similar to DNA microarray, protein microarray and antibody microarray. In chemical genetics research, they are routinely used for searching proteins that bind with specific chemical compounds, and in general drug discovery research, they provide a multiplex way to search potential drugs for therapeutic targets.There are three different forms of chemical compound microarrays based on the fabrication method. The first form is to covalently immobilize the organic compounds on the solid surface with diverse linking techniques; this platform is usually called Small Molecule Microarray, which is invented and advanced by Dr. Stuart Schreiber and colleagues [1]. The second form is to spot and dry organic compounds on the solid surface without immobilization, this platform has a commercial name as Micro Arrayed Compound Screening (µARCS), which is developed by scientists in Abbott Laboratories [2]. The last form is to spot organic compounds in a homogenous solution without immobilization and drying effect, this platform is developed by Dr. Scott Diamond [3] and later commercialized as DiscoveryDot technology by Reaction Biology Corporation [4].Polymer MicroarraysPolymer microarrays have been developed to allow screening for new polymeric materials to direct different tissue lineages. Research has also been directed towards studying the surface chemistry of these arrays to determine which surface chemistries control cell adhesion.".
- Chemical_compound_microarray thumbnail DiscoveryDot_Kinase_Profiling.jpg?width=300.
- Chemical_compound_microarray wikiPageExternalLink small_mol.html.
- Chemical_compound_microarray wikiPageExternalLink 12.
- Chemical_compound_microarray wikiPageExternalLink 48.
- Chemical_compound_microarray wikiPageExternalLink COCB_9_4.pdf.
- Chemical_compound_microarray wikiPageExternalLink oct2006.
- Chemical_compound_microarray wikiPageExternalLink art00005?token=004d15861b30d7627502b333e3568263c2b6f7e2a46762c47355d367034702e2e6e455f5498c6.
- Chemical_compound_microarray wikiPageExternalLink adt.2005.3.177.
- Chemical_compound_microarray wikiPageExternalLink 8721?ijkey=d5e57ca2c193e4de9f71357825d18eccb55c35c5.
- Chemical_compound_microarray wikiPageExternalLink www.reactionbiology.com.
- Chemical_compound_microarray wikiPageExternalLink ~diamond.
- Chemical_compound_microarray wikiPageID "5624034".
- Chemical_compound_microarray wikiPageRevisionID "586334824".
- Chemical_compound_microarray hasPhotoCollection Chemical_compound_microarray.
- Chemical_compound_microarray subject Category:Microarrays.
- Chemical_compound_microarray subject Category:Nanotechnology.
- Chemical_compound_microarray comment "A chemical compound microarray is a collection of organic chemical compounds spotted on a solid surface, such as glass and plastic. This microarray format is very similar to DNA microarray, protein microarray and antibody microarray.".
- Chemical_compound_microarray label "Chemical compound microarray".
- Chemical_compound_microarray sameAs m.0dwxn8.
- Chemical_compound_microarray sameAs Q5090450.
- Chemical_compound_microarray sameAs Q5090450.
- Chemical_compound_microarray wasDerivedFrom Chemical_compound_microarray?oldid=586334824.
- Chemical_compound_microarray depiction DiscoveryDot_Kinase_Profiling.jpg.
- Chemical_compound_microarray isPrimaryTopicOf Chemical_compound_microarray.
