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- Chemical_specificity abstract "Chemical specificity is the ability of a protein's binding site to bind specific ligands. The fewer ligands a protein can bind, the greater its specificity.Specificity has its technical basis as an experimental measurement in enzyme kinetics, where the strength of binding between a given protein and ligand can be described by a dissociation constant, which characterizes the balance between bound and unbound states for the protein-ligand system. In the context of a single enzyme and a pair of binding molecules, the two ligands can be compared as stronger or weaker ligands (for the enzyme) on the basis of their dissociation constants. (A lower value corresponds to a stronger binding.)Specificity for a set of ligands is unrelated to the ability of an enzyme to catalyze a given reaction, with the ligand as a substrate.If a given enzyme has a high chemical specificity, this means that the set of ligands to which it binds is limited, such that neither binding events nor catalysis can occur at an appreciable rate with additional molecules.An example of a protein-ligand pair whose binding activity can be described as highly specific is the antibody-antigen system. Conversely, an example of a protein-ligand system that can bind substrates and catalyze multiple reactions effectively is the Cytochrome P450 system, which can be considered a promiscuous enzyme due to its broad specificity for multiple ligands.".
- Chemical_specificity wikiPageID "529609".
- Chemical_specificity wikiPageRevisionID "560314756".
- Chemical_specificity hasPhotoCollection Chemical_specificity.
- Chemical_specificity subject Category:Chemical_bonding.
- Chemical_specificity subject Category:Proteins.
- Chemical_specificity type Abstraction100002137.
- Chemical_specificity type Chemical114806838.
- Chemical_specificity type Compound114818238.
- Chemical_specificity type Macromolecule114944888.
- Chemical_specificity type Material114580897.
- Chemical_specificity type Matter100020827.
- Chemical_specificity type Molecule114682133.
- Chemical_specificity type OrganicCompound114727670.
- Chemical_specificity type Part113809207.
- Chemical_specificity type PhysicalEntity100001930.
- Chemical_specificity type Protein114728724.
- Chemical_specificity type Proteins.
- Chemical_specificity type Relation100031921.
- Chemical_specificity type Substance100019613.
- Chemical_specificity type Thing100002452.
- Chemical_specificity type Unit109465459.
- Chemical_specificity comment "Chemical specificity is the ability of a protein's binding site to bind specific ligands. The fewer ligands a protein can bind, the greater its specificity.Specificity has its technical basis as an experimental measurement in enzyme kinetics, where the strength of binding between a given protein and ligand can be described by a dissociation constant, which characterizes the balance between bound and unbound states for the protein-ligand system.".
- Chemical_specificity label "Chemical specificity".
- Chemical_specificity sameAs m.02m0bs.
- Chemical_specificity sameAs Q5090496.
- Chemical_specificity sameAs Q5090496.
- Chemical_specificity sameAs Chemical_specificity.
- Chemical_specificity wasDerivedFrom Chemical_specificity?oldid=560314756.
- Chemical_specificity isPrimaryTopicOf Chemical_specificity.