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- Chevron_plot abstract "A chevron plot is a way of representing protein folding kinetic data in the presence of varying concentrations of denaturant that disrupts the protein's native tertiary structure. The plot is known as "chevron" plot because of the canonical v, or chevron shape observed when the logarithm of the observed relaxation rate is plotted as a function of the denaturant concentration. In a two-state system, folding and unfolding rates dominate the observed relaxation rates below and above the denaturation midpoint (Cm). This gives rise to the terminology of folding and unfolding arms for the limbs of the chevron. A priori information on the Cm of a protein can be obtained from equilibrium experiments. In fitting to a two-state model, the logarithm of the folding and unfolding rates is assumed to depend linearly on the denaturant concentration, thus resulting in the slopes mf and mu, called the folding and unfolding m-values, respectively (also called the kinetic m-values). The sum of the two rates is the observed relaxation rate. An agreement between equilibrium m-value and the absolute sum of the kinetic m-values is typically seen as a signature for two-state behavior. Most of the reported denaturation experiments have been carried out at 298 K with either urea or guanidinium chloride (GuHCl) as denaturants.".
- Chevron_plot thumbnail Chevron_plot.JPG?width=300.
- Chevron_plot wikiPageID "6736528".
- Chevron_plot wikiPageRevisionID "603782000".
- Chevron_plot hasPhotoCollection Chevron_plot.
- Chevron_plot subject Category:Protein_methods.
- Chevron_plot subject Category:Protein_structure.
- Chevron_plot type Ability105616246.
- Chevron_plot type Abstraction100002137.
- Chevron_plot type Cognition100023271.
- Chevron_plot type Know-how105616786.
- Chevron_plot type Method105660268.
- Chevron_plot type ProteinMethods.
- Chevron_plot type PsychologicalFeature100023100.
- Chevron_plot comment "A chevron plot is a way of representing protein folding kinetic data in the presence of varying concentrations of denaturant that disrupts the protein's native tertiary structure. The plot is known as "chevron" plot because of the canonical v, or chevron shape observed when the logarithm of the observed relaxation rate is plotted as a function of the denaturant concentration.".
- Chevron_plot label "Chevron plot".
- Chevron_plot sameAs m.0glcjk.
- Chevron_plot sameAs Q5094447.
- Chevron_plot sameAs Q5094447.
- Chevron_plot sameAs Chevron_plot.
- Chevron_plot wasDerivedFrom Chevron_plot?oldid=603782000.
- Chevron_plot depiction Chevron_plot.JPG.
- Chevron_plot isPrimaryTopicOf Chevron_plot.