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- Chronic_mountain_sickness abstract "Chronic Mountain Sickness (CMS) is a disease that can develop during extended time living at a high altitude. It is also known as "Monge's Disease", after its first description in 1925 by Carlos Monge. While acute mountain sickness is experienced shortly after ascent to high altitude, chronic mountain sickness may develop after many years of living at high altitude. In medicine, high altitude is defined as over 2500 metres (8200 ft), but most cases of CMS occur at over 3000 m (10000 ft). Recently it has been correlated with increased expression of the genes ANP32D and SENP1.Although CMS generally affects people native to altitudes higher than 3000m, it does not affect populations around the world equally. A recent study by Sahota and Panwar (2013)reviewed CMS prevalence rates around the world and found the highest rates were found in Andean countries of South America and the lowest rates in people native to the East African Mountains of Ethiopia. CMS prevalence rates from the study are summarized below: Ethiopia [3600m-4100m]: 0% Tibetan Plateau (Tibetans): 0.91% to 1.2% Indian Himalayas [3000m-4200m]: 4% to 7% Kyrgyzstan [3000m-4200m]: 4.6% Tibetan Plateau (Han Chinese): 5.6% La Paz, Bolivia [3600m]: 6% to 8% Bolivia: 8% to 10% Cerro de Pasco, Peru [4300m]: 14.8% to 18.2%CMS is characterised by polycythemia (with subsequent increased hematocrit) and hypoxemia which both improve on descent from altitude. CMS is believed to arise because of an excessive production of red blood cells, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs (V/Q mismatch). However, CMS is also considered an adaptation of pulmonary and heart disease to life under chronic hypoxia at altitude.The most frequent symptoms and signs of CMS are headache, dizziness, tinnitus, breathlessness, palpitations, sleep disturbance, fatigue, anorexia, mental confusion, cyanosis, and dilation of veins.Clinical diagnosis by laboratory indicators have ranges of: Hb > 200 g/L, Hct > 65%, and arterial oxygen saturation (SaO2) < 85% in both genders.Treatment involves descent from altitude, where the symptoms will diminish and the hematocrit return to normal slowly. Acute treatment at altitude involves bleeding (phlebotomy), removal of circulating blood, to reduce the hematocrit; however this is not ideal for extended periods.".
- Chronic_mountain_sickness diseasesdb "29615".
- Chronic_mountain_sickness icd10 "T70.2".
- Chronic_mountain_sickness icd9 "E902.0".
- Chronic_mountain_sickness wikiPageExternalLink oxygen_carriage.php.
- Chronic_mountain_sickness wikiPageExternalLink www.altitudeclinic.com.
- Chronic_mountain_sickness wikiPageExternalLink CMSchronichypoxia.pdf.
- Chronic_mountain_sickness wikiPageID "4092962".
- Chronic_mountain_sickness wikiPageRevisionID "605123993".
- Chronic_mountain_sickness diseasesdb "29615".
- Chronic_mountain_sickness hasPhotoCollection Chronic_mountain_sickness.
- Chronic_mountain_sickness icd "E902.0".
- Chronic_mountain_sickness icd "T70.2".
- Chronic_mountain_sickness wordnet_type synset-disease-noun-1.
- Chronic_mountain_sickness subject Category:Effects_of_external_causes.
- Chronic_mountain_sickness subject Category:Mountaineering_and_health.
- Chronic_mountain_sickness type Consequence111410625.
- Chronic_mountain_sickness type EffectsOfExternalCauses.
- Chronic_mountain_sickness type Phenomenon100034213.
- Chronic_mountain_sickness type PhysicalEntity100001930.
- Chronic_mountain_sickness type Process100029677.
- Chronic_mountain_sickness type Disease.
- Chronic_mountain_sickness type AilmentCondition.
- Chronic_mountain_sickness type Situation.
- Chronic_mountain_sickness comment "Chronic Mountain Sickness (CMS) is a disease that can develop during extended time living at a high altitude. It is also known as "Monge's Disease", after its first description in 1925 by Carlos Monge. While acute mountain sickness is experienced shortly after ascent to high altitude, chronic mountain sickness may develop after many years of living at high altitude. In medicine, high altitude is defined as over 2500 metres (8200 ft), but most cases of CMS occur at over 3000 m (10000 ft).".
- Chronic_mountain_sickness label "Chronic mountain sickness".
- Chronic_mountain_sickness label "Mal de montaña crónico".
- Chronic_mountain_sickness label "慢性高原病".
- Chronic_mountain_sickness sameAs Mal_de_montaña_crónico.
- Chronic_mountain_sickness sameAs m.0bhm4g.
- Chronic_mountain_sickness sameAs Q582189.
- Chronic_mountain_sickness sameAs Q582189.
- Chronic_mountain_sickness sameAs Chronic_mountain_sickness.
- Chronic_mountain_sickness wasDerivedFrom Chronic_mountain_sickness?oldid=605123993.
- Chronic_mountain_sickness isPrimaryTopicOf Chronic_mountain_sickness.