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- Clodronic_acid abstract "Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa. An Italian study compared the analgesic effect of clodronic acid versus acetaminophen in reumatic condition related pain. Study result show a reduction in pain in favor of clodronic acid that provided more analgesia than 3 grams/day of acetaminophen. Clodronate is also used in experimental medicine to selectively deplete macrophages. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent.".
- Clodronic_acid atcPrefix "M05".
- Clodronic_acid atcSuffix "BA02".
- Clodronic_acid casNumber "10596-23-3".
- Clodronic_acid chEBI "110423".
- Clodronic_acid drugbank "DB00720".
- Clodronic_acid fdaUniiCode "0813BZ6866".
- Clodronic_acid iupacName "(dichloro-phosphono-methyl)phosphonic acid".
- Clodronic_acid pubchem "25419".
- Clodronic_acid thumbnail Clodronic_acid.png?width=300.
- Clodronic_acid wikiPageID "12115953".
- Clodronic_acid wikiPageRevisionID "600108129".
- Clodronic_acid atcPrefix "M05".
- Clodronic_acid atcSuffix "BA02".
- Clodronic_acid c "1".
- Clodronic_acid casNumber "10596".
- Clodronic_acid chebi "110423".
- Clodronic_acid chembl "12318".
- Clodronic_acid chemspiderid "23731".
- Clodronic_acid cl "2".
- Clodronic_acid drugbank "DB00720".
- Clodronic_acid h "4".
- Clodronic_acid hasPhotoCollection Clodronic_acid.
- Clodronic_acid inchi "1".
- Clodronic_acid inchikey "ACSIXWWBWUQEHA-UHFFFAOYAO".
- Clodronic_acid iupacName "phosphonic acid".
- Clodronic_acid kegg "D03545".
- Clodronic_acid molecularWeight "244.892".
- Clodronic_acid o "6".
- Clodronic_acid p "2".
- Clodronic_acid pubchem "25419".
- Clodronic_acid smiles "ClCPO".
- Clodronic_acid stdinchi "1".
- Clodronic_acid stdinchikey "ACSIXWWBWUQEHA-UHFFFAOYSA-N".
- Clodronic_acid unii "813".
- Clodronic_acid verifiedrevid "476996903".
- Clodronic_acid subject Category:Bisphosphonates.
- Clodronic_acid type Drug.
- Clodronic_acid type DrugProduct.
- Clodronic_acid type FunctionalSubstance.
- Clodronic_acid comment "Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa.".
- Clodronic_acid label "Acide clodronique".
- Clodronic_acid label "Acido clodronico".
- Clodronic_acid label "Clodronic acid".
- Clodronic_acid label "Клодроновая кислота".
- Clodronic_acid label "氯膦酸".
- Clodronic_acid sameAs Acide_clodronique.
- Clodronic_acid sameAs Acido_clodronico.
- Clodronic_acid sameAs m.02vq99c.
- Clodronic_acid sameAs Q2341200.
- Clodronic_acid sameAs Q2341200.
- Clodronic_acid sameAs DB00720.
- Clodronic_acid wasDerivedFrom Clodronic_acid?oldid=600108129.
- Clodronic_acid depiction Clodronic_acid.png.
- Clodronic_acid isPrimaryTopicOf Clodronic_acid.
