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- Clostridium_difficile_toxin_A abstract "Clostridium difficile toxin A (TcdA) is a toxin generated by Clostridium difficile. It is similar to Clostridium difficile Toxin B. The toxins are the main virulence factors produced by the gram positive, anaerobic, Clostridium difficile bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis.TcdA is one of the largest bacterial toxins known. With a molecular mass of 308kDa, it is usually described as a potent enterotoxin, but it also has some activity as a cytotoxin. The toxin acts by modifying host cell GTPase proteins by glucosylation, leading to changes in cellular activities. Risk factors for C. difficile infection include antibiotic treatment, which can disrupt normal intestinal microbiota and lead to colonization of C. difficile bacteria.".
- Clostridium_difficile_toxin_A thumbnail Clostridium_difficile_01.jpg?width=300.
- Clostridium_difficile_toxin_A wikiPageID "20637118".
- Clostridium_difficile_toxin_A wikiPageRevisionID "593798954".
- Clostridium_difficile_toxin_A altsymbols "tcdA".
- Clostridium_difficile_toxin_A chromosome "genome".
- Clostridium_difficile_toxin_A ecnumber "2.4".
- Clostridium_difficile_toxin_A entrezchromosome "NC_009089.1".
- Clostridium_difficile_toxin_A entrezgene "4914076".
- Clostridium_difficile_toxin_A genlocEnd "805194".
- Clostridium_difficile_toxin_A genlocStart "794622".
- Clostridium_difficile_toxin_A hasPhotoCollection Clostridium_difficile_toxin_A.
- Clostridium_difficile_toxin_A name "Toxin A".
- Clostridium_difficile_toxin_A organism "Clostridium difficile".
- Clostridium_difficile_toxin_A refseqprotein "YP_001087137.1".
- Clostridium_difficile_toxin_A symbol "toxA".
- Clostridium_difficile_toxin_A taxid "1496".
- Clostridium_difficile_toxin_A uniprot "P16154".
- Clostridium_difficile_toxin_A subject Category:Bacterial_toxins.
- Clostridium_difficile_toxin_A type BacterialToxin115034939.
- Clostridium_difficile_toxin_A type BacterialToxins.
- Clostridium_difficile_toxin_A type Matter100020827.
- Clostridium_difficile_toxin_A type PhysicalEntity100001930.
- Clostridium_difficile_toxin_A type Poison115032376.
- Clostridium_difficile_toxin_A type Substance100020090.
- Clostridium_difficile_toxin_A type Toxin115034074.
- Clostridium_difficile_toxin_A type Toxins.
- Clostridium_difficile_toxin_A comment "Clostridium difficile toxin A (TcdA) is a toxin generated by Clostridium difficile. It is similar to Clostridium difficile Toxin B. The toxins are the main virulence factors produced by the gram positive, anaerobic, Clostridium difficile bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis.TcdA is one of the largest bacterial toxins known.".
- Clostridium_difficile_toxin_A label "Clostridium difficile toxin A".
- Clostridium_difficile_toxin_A sameAs m.0520gy7.
- Clostridium_difficile_toxin_A sameAs Q5135488.
- Clostridium_difficile_toxin_A sameAs Q5135488.
- Clostridium_difficile_toxin_A sameAs Clostridium_difficile_toxin_A.
- Clostridium_difficile_toxin_A wasDerivedFrom Clostridium_difficile_toxin_A?oldid=593798954.
- Clostridium_difficile_toxin_A depiction Clostridium_difficile_01.jpg.
- Clostridium_difficile_toxin_A isPrimaryTopicOf Clostridium_difficile_toxin_A.
