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- Clostridium_enterotoxin abstract "Clostridium enterotoxins are toxins produced by Clostridium species.Clostridial species are one of the major causes of food poisoning/gastro-intestinal illnesses. They are anaerobic, gram-positive, spore-forming rods that occur naturally in the soil. Among the family are: Clostridium botulinum, which produces one of the most potent toxins in existence; Clostridium tetani, causative agent of tetanus; and Clostridium perfringens, commonly found in wound infections and diarrhea cases. The use of toxins to damage the host is a method deployed by many bacterial pathogens.The major virulence factor of C. perfringens is the CPE enterotoxin, which is secreted upon invasion of the host gut, and contributes to food poisoning and other gastrointestinal illnesses. It has a molecular weight of 35.3kDa, and is responsible for the disintegration of tight junctions between endothelial cells in the gut. This mechanism is mediated by host claudin-3 and claudin-4 receptors, situated at the tight junctionsClostridium enterotoxin is a nine-stranded beta sheet sandwich in shape. It has been determined that it is very similar to other spore-forming bacteria. The PFAM ID is a clenterotox. The binding site is between beta sheets eight and nine. This allows the human claudin-3,4,6,7,8 and 14 to bind but not 1,2,5, and 10. The way the protein work is it destroys the cell membranes structure of animals by binding to claudin family proteins. These are components of tight junctions of the epithelial cell membrane.".
- Clostridium_enterotoxin symbol "Clenterotox".
- Clostridium_enterotoxin thumbnail 2QUO.pdb.jpg?width=300.
- Clostridium_enterotoxin wikiPageID "20131020".
- Clostridium_enterotoxin wikiPageRevisionID "603364909".
- Clostridium_enterotoxin caption "Crystal Structure of C terminal fragment of Clostridium perfringens enterotoxin".
- Clostridium_enterotoxin hasPhotoCollection Clostridium_enterotoxin.
- Clostridium_enterotoxin interpro "IPR003897".
- Clostridium_enterotoxin name "Clostridium enterotoxin".
- Clostridium_enterotoxin pfam "PF03505".
- Clostridium_enterotoxin symbol "Clenterotox".
- Clostridium_enterotoxin tcdb "1".
- Clostridium_enterotoxin subject Category:Bacterial_toxins.
- Clostridium_enterotoxin subject Category:Gas_gangrene.
- Clostridium_enterotoxin type BacterialToxin115034939.
- Clostridium_enterotoxin type BacterialToxins.
- Clostridium_enterotoxin type Matter100020827.
- Clostridium_enterotoxin type PhysicalEntity100001930.
- Clostridium_enterotoxin type Poison115032376.
- Clostridium_enterotoxin type Substance100020090.
- Clostridium_enterotoxin type Toxin115034074.
- Clostridium_enterotoxin type Biomolecule.
- Clostridium_enterotoxin type Protein.
- Clostridium_enterotoxin type BiologicalObject.
- Clostridium_enterotoxin comment "Clostridium enterotoxins are toxins produced by Clostridium species.Clostridial species are one of the major causes of food poisoning/gastro-intestinal illnesses. They are anaerobic, gram-positive, spore-forming rods that occur naturally in the soil. Among the family are: Clostridium botulinum, which produces one of the most potent toxins in existence; Clostridium tetani, causative agent of tetanus; and Clostridium perfringens, commonly found in wound infections and diarrhea cases.".
- Clostridium_enterotoxin label "Clostridium enterotoxin".
- Clostridium_enterotoxin label "ذيفان المطثية الحاطمة المعوي".
- Clostridium_enterotoxin sameAs m.04y9ntg.
- Clostridium_enterotoxin sameAs Q5135493.
- Clostridium_enterotoxin sameAs Q5135493.
- Clostridium_enterotoxin sameAs Clostridium_enterotoxin.
- Clostridium_enterotoxin wasDerivedFrom Clostridium_enterotoxin?oldid=603364909.
- Clostridium_enterotoxin depiction 2QUO.pdb.jpg.
- Clostridium_enterotoxin isPrimaryTopicOf Clostridium_enterotoxin.