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- Complement_factor_B abstract "Complement factor B is a protein that in humans is encoded by the CFB gene.This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.".
- Complement_factor_B entrezgene "629".
- Complement_factor_B thumbnail Droga_alternatywna.png?width=300.
- Complement_factor_B wikiPageExternalLink merops.cgi?id=S01.196.
- Complement_factor_B wikiPageExternalLink NBK1367.
- Complement_factor_B wikiPageExternalLink 277400,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926.
- Complement_factor_B wikiPageID "5989673".
- Complement_factor_B wikiPageRevisionID "544469363".
- Complement_factor_B hasPhotoCollection Complement_factor_B.
- Complement_factor_B requireManualInspection "no".
- Complement_factor_B summaryText "This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.".
- Complement_factor_B updateCitations "yes".
- Complement_factor_B updatePage "yes".
- Complement_factor_B updateProteinBox "yes".
- Complement_factor_B updateSummary "yes".
- Complement_factor_B subject Category:Complement_system.
- Complement_factor_B type Biomolecule.
- Complement_factor_B type Protein.
- Complement_factor_B type BiologicalObject.
- Complement_factor_B comment "Complement factor B is a protein that in humans is encoded by the CFB gene.This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb.".
- Complement_factor_B label "Complement factor B".
- Complement_factor_B label "Czynnik B".
- Complement_factor_B sameAs Faktor_komplemen_B.
- Complement_factor_B sameAs Czynnik_B.
- Complement_factor_B sameAs m.0fjf4y.
- Complement_factor_B sameAs Q4256414.
- Complement_factor_B sameAs Q4256414.
- Complement_factor_B sameAs 3095.
- Complement_factor_B sameAs 3346.
- Complement_factor_B wasDerivedFrom Complement_factor_B?oldid=544469363.
- Complement_factor_B depiction Droga_alternatywna.png.
- Complement_factor_B isPrimaryTopicOf Complement_factor_B.
