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- Cycloserine abstract "Cycloserine (4-amino-3-isoxazolidinone) is a drug sold under the brand name Seromycin. It is an antibiotic effective against Mycobacterium tuberculosis. Since the discovery that cycloserine is able to penetrate into the central nervous system, numerous studies have been conducted to assess the efficacy of cycloserine for psychiatric disorders. It has been found to be effective in the treatment of some neurological disorders, due to its effect as a selective partial agonist of the N-methyl-D-aspartic acid (NMDA) glutamatergic receptors found in the basolateral nucleus of the amygdala. Specifically, cycloserine affects the glycine-binding sites which are important for opening these NMDA channels. Cycloserine is stable under basic conditions, with the greatest stability at pH = 11.5. Under mildly acidic conditions, ite breaks down into hydroxylamine and D-serine, whereas under prolonged hydrolysis, it breaks down into hydroxylamine and DL-serine.The name "cycloserine" is a misnomer because the compound has an extra nitrogen atom compared to serine. (It also has one fewer oxygen atoms and one fewer hydrogen atoms than serine.)".
- Cycloserine atcPrefix "J04".
- Cycloserine atcSuffix "AB01".
- Cycloserine casNumber "339-72-0".
- Cycloserine casNumber "68-41-7".
- Cycloserine chEBI "40009".
- Cycloserine drugbank "DB00260".
- Cycloserine fdaUniiCode "95IK5KI84Z".
- Cycloserine iupacName "(4S)-4-Amino-1,2-oxazolidin-3-one".
- Cycloserine iupacName "(R)-4-Amino-1,2-oxazolidin-3-one".
- Cycloserine pubchem "449215".
- Cycloserine pubchem "6234".
- Cycloserine thumbnail Cycloserine.svg?width=300.
- Cycloserine wikiPageID "4423825".
- Cycloserine wikiPageRevisionID "602398351".
- Cycloserine atcPrefix "J04".
- Cycloserine atcSuffix "AB01".
- Cycloserine bioavailability "~70% to 90%".
- Cycloserine c "3".
- Cycloserine casNumber "339".
- Cycloserine casNumber "68".
- Cycloserine chebi "40009".
- Cycloserine chembl "771".
- Cycloserine chemicalFormula "C3H6N2O2".
- Cycloserine chemspiderid "395808".
- Cycloserine chemspiderid "5998".
- Cycloserine drugbank "DB00260".
- Cycloserine eliminationHalfLife "36000.0".
- Cycloserine excretion "Renal".
- Cycloserine h "6".
- Cycloserine hasPhotoCollection Cycloserine.
- Cycloserine image "Cycloserine ball-and-stick.png".
- Cycloserine inchi "1".
- Cycloserine inchikey "DYDCUQKUCUHJBH-REOHCLBHBD".
- Cycloserine inchikey "DYDCUQKUCUHJBH-UWTATZPHBN".
- Cycloserine iupacName "-4".
- Cycloserine kegg "D00877".
- Cycloserine metabolism "Hepatic".
- Cycloserine molecularWeight "102.092".
- Cycloserine n "2".
- Cycloserine niaidChemdb "7654".
- Cycloserine o "2".
- Cycloserine pregnancyCategory "C".
- Cycloserine pubchem "449215".
- Cycloserine pubchem "6234".
- Cycloserine smiles "C1[C@@H]N".
- Cycloserine smiles "O=C1NOC[C@H]1N".
- Cycloserine stdinchi "1".
- Cycloserine stdinchikey "DYDCUQKUCUHJBH-REOHCLBHSA-N".
- Cycloserine stdinchikey "DYDCUQKUCUHJBH-UWTATZPHSA-N".
- Cycloserine tradename "Seromycin".
- Cycloserine unii "95".
- Cycloserine verifiedrevid "460111047".
- Cycloserine watchedfields "changed".
- Cycloserine subject Category:Antibiotics.
- Cycloserine subject Category:Isoxazolidinones.
- Cycloserine subject Category:Lactams.
- Cycloserine subject Category:NMDA_receptor_agonists.
- Cycloserine subject Category:Tuberculosis.
- Cycloserine subject Category:World_Health_Organization_essential_medicines.
- Cycloserine type Drug.
- Cycloserine type DrugProduct.
- Cycloserine type FunctionalSubstance.
- Cycloserine comment "Cycloserine (4-amino-3-isoxazolidinone) is a drug sold under the brand name Seromycin. It is an antibiotic effective against Mycobacterium tuberculosis. Since the discovery that cycloserine is able to penetrate into the central nervous system, numerous studies have been conducted to assess the efficacy of cycloserine for psychiatric disorders.".
- Cycloserine label "Cicloserina".
- Cycloserine label "Cicloserina".
- Cycloserine label "Cycloserin".
- Cycloserine label "Cycloserine".
- Cycloserine label "Cyclosérine".
- Cycloserine label "Cykloseryna".
- Cycloserine label "Oxamicina".
- Cycloserine label "Циклосерин".
- Cycloserine sameAs Cycloserin.
- Cycloserine sameAs Cicloserina.
- Cycloserine sameAs Cyclosérine.
- Cycloserine sameAs Cicloserina.
- Cycloserine sameAs 사이클로세린.
- Cycloserine sameAs Cykloseryna.
- Cycloserine sameAs Oxamicina.
- Cycloserine sameAs m.0c1kpb.
- Cycloserine sameAs Q418508.
- Cycloserine sameAs Q418508.
- Cycloserine sameAs Cycloserine.
- Cycloserine sameAs DB00260.
- Cycloserine sameAs 401.
- Cycloserine wasDerivedFrom Cycloserine?oldid=602398351.
- Cycloserine depiction Cycloserine.svg.
- Cycloserine isPrimaryTopicOf Cycloserine.
