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- Cyclothiazide abstract "Cyclothiazide (Anhydron, Acquirel, Doburil, Fluidil, Renazide, Tensodiural, Valmiran) is a benzothiadiazide (thiazide) diuretic and antihypertensive that was originally introduced in the United States in 1963 by Eli Lilly and was subsequently also marketed in Europe and Japan. Related drugs include diazoxide, hydrochlorothiazide, and chlorothiazide.In 1993, it was discovered that cyclothiazide is a positive allosteric modulator of the AMPA receptor, capable of reducing or essentially eliminating rapid desensitization of the receptor, and potentiating glutamate currents by as much as 18-fold at the highest concentration tested (100 μM). Additionally, in 2003, cyclothiazide was also found to act as a GABAA receptor negative allosteric modulator, potently inhibiting GABAA-mediated currents. In animals it is a powerful convulsant, robustly enhancing epileptiform activity and inducing seizures, but without producing any apparent neuronal death.".
- Cyclothiazide atcPrefix "C03".
- Cyclothiazide atcSuffix "AA09".
- Cyclothiazide casNumber "2259-96-3".
- Cyclothiazide drugbank "DB00606".
- Cyclothiazide fdaUniiCode "P71U09G5BW".
- Cyclothiazide iupacName "3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide".
- Cyclothiazide pubchem "2910".
- Cyclothiazide thumbnail Cyclothiazide.png?width=300.
- Cyclothiazide wikiPageID "18493625".
- Cyclothiazide wikiPageRevisionID "593929473".
- Cyclothiazide atcPrefix "3.0".
- Cyclothiazide atcSuffix "AA09".
- Cyclothiazide c "14".
- Cyclothiazide casNumber "2259".
- Cyclothiazide chembl "61593".
- Cyclothiazide chemspiderid "4535011".
- Cyclothiazide cl "1".
- Cyclothiazide drugbank "DB00606".
- Cyclothiazide h "16".
- Cyclothiazide hasPhotoCollection Cyclothiazide.
- Cyclothiazide inchi "1".
- Cyclothiazide inchikey "BOCUKUHCLICSIY-UHFFFAOYAY".
- Cyclothiazide iupacName "3".
- Cyclothiazide kegg "D01256".
- Cyclothiazide legalStatus "Rx-only".
- Cyclothiazide molecularWeight "389.88".
- Cyclothiazide n "3".
- Cyclothiazide o "4".
- Cyclothiazide pubchem "2910".
- Cyclothiazide s "2".
- Cyclothiazide smiles "O=SN".
- Cyclothiazide stdinchi "1".
- Cyclothiazide stdinchikey "BOCUKUHCLICSIY-QJWLJZLASA-N".
- Cyclothiazide unii "P71U09G5BW".
- Cyclothiazide verifiedfields "changed".
- Cyclothiazide verifiedrevid "477166277".
- Cyclothiazide subject Category:AMPA_receptor_modulators.
- Cyclothiazide subject Category:Benzothiadiazines.
- Cyclothiazide subject Category:Diuretics.
- Cyclothiazide subject Category:Organochlorides.
- Cyclothiazide subject Category:Sulfonamides.
- Cyclothiazide type Agent114778436.
- Cyclothiazide type Antibacterial102716205.
- Cyclothiazide type CausalAgent100007347.
- Cyclothiazide type DiureticDrug103214670.
- Cyclothiazide type Diuretics.
- Cyclothiazide type Drug103247620.
- Cyclothiazide type Matter100020827.
- Cyclothiazide type Medicine103740161.
- Cyclothiazide type PhysicalEntity100001930.
- Cyclothiazide type Substance100020090.
- Cyclothiazide type SulfaDrug104352070.
- Cyclothiazide type Sulfonamides.
- Cyclothiazide type Drug.
- Cyclothiazide type DrugProduct.
- Cyclothiazide type FunctionalSubstance.
- Cyclothiazide comment "Cyclothiazide (Anhydron, Acquirel, Doburil, Fluidil, Renazide, Tensodiural, Valmiran) is a benzothiadiazide (thiazide) diuretic and antihypertensive that was originally introduced in the United States in 1963 by Eli Lilly and was subsequently also marketed in Europe and Japan.".
- Cyclothiazide label "Ciclotiazida".
- Cyclothiazide label "Cyclothiazide".
- Cyclothiazide sameAs Ciclotiazida.
- Cyclothiazide sameAs m.04f3h88.
- Cyclothiazide sameAs Q5199066.
- Cyclothiazide sameAs Q5199066.
- Cyclothiazide sameAs DB00606.
- Cyclothiazide sameAs Cyclothiazide.
- Cyclothiazide wasDerivedFrom Cyclothiazide?oldid=593929473.
- Cyclothiazide depiction Cyclothiazide.png.
- Cyclothiazide isPrimaryTopicOf Cyclothiazide.
