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- DCTN2 abstract "Dynactin subunit 2 is a protein that in humans is encoded by the DCTN2 gene.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.".
- DCTN2 entrezgene "10540".
- DCTN2 wikiPageID "14762803".
- DCTN2 wikiPageRevisionID "590939292".
- DCTN2 hasPhotoCollection DCTN2.
- DCTN2 requireManualInspection "no".
- DCTN2 summaryText "This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit of dynactin and may affix p150 in place.".
- DCTN2 updateCitations "yes".
- DCTN2 updatePage "yes".
- DCTN2 updateProteinBox "yes".
- DCTN2 updateSummary "yes".
- DCTN2 type Biomolecule.
- DCTN2 type Protein.
- DCTN2 type BiologicalObject.
- DCTN2 comment "Dynactin subunit 2 is a protein that in humans is encoded by the DCTN2 gene.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.".
- DCTN2 label "DCTN2".
- DCTN2 sameAs m.03gx44x.
- DCTN2 sameAs Q5204552.
- DCTN2 sameAs Q5204552.
- DCTN2 wasDerivedFrom DCTN2?oldid=590939292.
- DCTN2 isPrimaryTopicOf DCTN2.