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- DNA_damage_theory_of_aging abstract "The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).In humans and other mammals, DNA damage occurs frequently and DNA repair processes have evolved to compensate. In estimates made for mice, on average approximately 1,500 to 7,000 DNA lesions occur per hour in each mouse cell, or about 36,000 to 160,000 per cell per day (Vilenchik & Knudson 2000). In any cell some DNA damage may remain despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, such as cells in the brain, skeletal and cardiac muscle.".
- DNA_damage_theory_of_aging wikiPageExternalLink product_info.php?products_id=43247.
- DNA_damage_theory_of_aging wikiPageID "17062920".
- DNA_damage_theory_of_aging wikiPageRevisionID "593544838".
- DNA_damage_theory_of_aging hasPhotoCollection DNA_damage_theory_of_aging.
- DNA_damage_theory_of_aging subject Category:Ageing.
- DNA_damage_theory_of_aging subject Category:DNA.
- DNA_damage_theory_of_aging subject Category:Programmed_cell_death.
- DNA_damage_theory_of_aging subject Category:Proximate_theories_of_biological_aging.
- DNA_damage_theory_of_aging subject Category:Senescence.
- DNA_damage_theory_of_aging subject Category:Theories_of_aging.
- DNA_damage_theory_of_aging subject Category:Theories_of_biological_aging.
- DNA_damage_theory_of_aging comment "The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis.".
- DNA_damage_theory_of_aging label "DNA damage theory of aging".
- DNA_damage_theory_of_aging sameAs m.0417458.
- DNA_damage_theory_of_aging sameAs Q5205751.
- DNA_damage_theory_of_aging sameAs Q5205751.
- DNA_damage_theory_of_aging wasDerivedFrom DNA_damage_theory_of_aging?oldid=593544838.
- DNA_damage_theory_of_aging isPrimaryTopicOf DNA_damage_theory_of_aging.