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- DNA_re-replication abstract "DNA re-replication (or simply rereplication) is an undesirable and possibly fatal occurrence in eukaryotic cells in which the genome is replicated more than once per cell cycle. Rereplication is believed to lead to genomic instability and has been implicated in the pathologies of a variety of human cancers. To prevent rereplication, eukaryotic cells have evolved multiple, overlapping mechanisms to inhibit chromosomal DNA from being partially or fully rereplicated in a given cell cycle. These control mechanisms rely on cyclin-dependent kinase (CDK) activity. DNA replication control mechanisms cooperate to prevent the relicensing of replication origins and to activate cell cycle and DNA damage checkpoints. DNA rereplication must be strictly regulated to ensure that genomic information is faithfully transmitted through successive generations.".
- DNA_re-replication thumbnail Origin_Licensing.png?width=300.
- DNA_re-replication wikiPageID "34086352".
- DNA_re-replication wikiPageRevisionID "600897428".
- DNA_re-replication hasPhotoCollection DNA_re-replication.
- DNA_re-replication subject Category:Cell_biology.
- DNA_re-replication subject Category:Cell_cycle.
- DNA_re-replication comment "DNA re-replication (or simply rereplication) is an undesirable and possibly fatal occurrence in eukaryotic cells in which the genome is replicated more than once per cell cycle. Rereplication is believed to lead to genomic instability and has been implicated in the pathologies of a variety of human cancers. To prevent rereplication, eukaryotic cells have evolved multiple, overlapping mechanisms to inhibit chromosomal DNA from being partially or fully rereplicated in a given cell cycle.".
- DNA_re-replication label "DNA re-replication".
- DNA_re-replication sameAs m.0hrcslm.
- DNA_re-replication sameAs Q5205768.
- DNA_re-replication sameAs Q5205768.
- DNA_re-replication wasDerivedFrom DNA_re-replication?oldid=600897428.
- DNA_re-replication depiction Origin_Licensing.png.
- DNA_re-replication isPrimaryTopicOf DNA_re-replication.