Matches in DBpedia 2014 for { <http://dbpedia.org/resource/DPH5> ?p ?o. }
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- DPH5 abstract "Diphthine synthase is an enzyme that in humans is encoded by the DPH5 gene.This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.".
- DPH5 entrezgene "51611".
- DPH5 wikiPageID "15073076".
- DPH5 wikiPageRevisionID "591060337".
- DPH5 hasPhotoCollection DPH5.
- DPH5 requireManualInspection "no".
- DPH5 summaryText "This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.".
- DPH5 updateCitations "yes".
- DPH5 updatePage "yes".
- DPH5 updateProteinBox "yes".
- DPH5 updateSummary "yes".
- DPH5 type Biomolecule.
- DPH5 type Protein.
- DPH5 type BiologicalObject.
- DPH5 comment "Diphthine synthase is an enzyme that in humans is encoded by the DPH5 gene.This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis.".
- DPH5 label "DPH5".
- DPH5 sameAs m.03hgmrn.
- DPH5 sameAs Q5205927.
- DPH5 sameAs Q5205927.
- DPH5 wasDerivedFrom DPH5?oldid=591060337.
- DPH5 isPrimaryTopicOf DPH5.