Matches in DBpedia 2014 for { <http://dbpedia.org/resource/DUSP1> ?p ?o. }
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- DUSP1 abstract "Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.".
- DUSP1 entrezgene "1843".
- DUSP1 wikiPageID "14144697".
- DUSP1 wikiPageRevisionID "591118678".
- DUSP1 hasPhotoCollection DUSP1.
- DUSP1 requireManualInspection "no".
- DUSP1 summaryText "--05-01".
- DUSP1 updateCitations "yes".
- DUSP1 updatePage "yes".
- DUSP1 updateProteinBox "yes".
- DUSP1 updateSummary "yes".
- DUSP1 type Biomolecule.
- DUSP1 type Protein.
- DUSP1 type BiologicalObject.
- DUSP1 comment "Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus.".
- DUSP1 label "DUSP1".
- DUSP1 label "DUSP1".
- DUSP1 sameAs DUSP1.
- DUSP1 sameAs m.03cvzyd.
- DUSP1 sameAs Q5206306.
- DUSP1 sameAs Q5206306.
- DUSP1 wasDerivedFrom DUSP1?oldid=591118678.
- DUSP1 isPrimaryTopicOf DUSP1.