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- Deamidation abstract "Deamidation is a chemical reaction in which an amide functional group is removed from an organic compound. In biochemistry, the reaction is important in the degradation of proteins because it damages the amide-containing side chains of the amino acids asparagine and glutamine.In the biochemical deamidation reaction, the side chain of an asparagine attacks the following peptide group (in black at top right of Figure), forming a symmetric succinimide intermediate (in red). The symmetry of the intermediate results in two products of its hydrolysis, either aspartate (in black at left) or in isoaspartate, which is a beta amino acid (in green at bottom right). This process is considered a deamidation because the amide in the asparagine side chain is replaced by a carboxylate group. However, a similar reaction can occur in aspartate side chains, yielding a partial conversion to isoaspartate.".
- Deamidation thumbnail Deamidation_Asn_Gly.png?width=300.
- Deamidation wikiPageID "5110843".
- Deamidation wikiPageRevisionID "541677244".
- Deamidation hasPhotoCollection Deamidation.
- Deamidation subject Category:Substitution_reactions.
- Deamidation type ChemicalProcess113446390.
- Deamidation type ChemicalReaction113447361.
- Deamidation type NaturalProcess113518963.
- Deamidation type PhysicalEntity100001930.
- Deamidation type Process100029677.
- Deamidation type SubstitutionReactions.
- Deamidation comment "Deamidation is a chemical reaction in which an amide functional group is removed from an organic compound. In biochemistry, the reaction is important in the degradation of proteins because it damages the amide-containing side chains of the amino acids asparagine and glutamine.In the biochemical deamidation reaction, the side chain of an asparagine attacks the following peptide group (in black at top right of Figure), forming a symmetric succinimide intermediate (in red).".
- Deamidation label "Deamidation".
- Deamidation label "脱アミド".
- Deamidation sameAs 脱アミド.
- Deamidation sameAs m.0d33f7.
- Deamidation sameAs Q4859711.
- Deamidation sameAs Q4859711.
- Deamidation sameAs Deamidation.
- Deamidation wasDerivedFrom Deamidation?oldid=541677244.
- Deamidation depiction Deamidation_Asn_Gly.png.
- Deamidation isPrimaryTopicOf Deamidation.
