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- Demecolcine abstract "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.In animal cloning procedures Demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.".
- Demecolcine atcPrefix "L01".
- Demecolcine atcSuffix "CC01".
- Demecolcine casNumber "477-30-5".
- Demecolcine fdaUniiCode "Z01IVE25KI".
- Demecolcine iupacName "(S)-1,2,3,10-Tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one".
- Demecolcine pubchem "2832".
- Demecolcine thumbnail Demecolcine.png?width=300.
- Demecolcine wikiPageID "20362448".
- Demecolcine wikiPageRevisionID "567923123".
- Demecolcine atcPrefix "L01".
- Demecolcine atcSuffix "CC01".
- Demecolcine c "21".
- Demecolcine casNumber "477".
- Demecolcine chembl "312862".
- Demecolcine chemspiderid "191135".
- Demecolcine h "25".
- Demecolcine hasPhotoCollection Demecolcine.
- Demecolcine inchi "1".
- Demecolcine inchikey "NNJPGOLRFBJNIW-HNNXBMFYBY".
- Demecolcine iupacName "-12310".
- Demecolcine molecularWeight "371.43".
- Demecolcine n "1".
- Demecolcine o "5".
- Demecolcine pubchem "2832".
- Demecolcine smiles "O=C/1C=C/C=C2\C[C@@H]CCc3c2cccc3".
- Demecolcine stdinchi "1".
- Demecolcine stdinchikey "NNJPGOLRFBJNIW-HNNXBMFYSA-N".
- Demecolcine unii "Z01IVE25KI".
- Demecolcine verifiedrevid "414414817".
- Demecolcine watchedfields "changed".
- Demecolcine subject Category:Alkaloids.
- Demecolcine subject Category:Heptalenes.
- Demecolcine subject Category:Ketones.
- Demecolcine subject Category:Microtubule_inhibitors.
- Demecolcine subject Category:Phenol_ethers.
- Demecolcine type Abstraction100002137.
- Demecolcine type Alkaloid114712692.
- Demecolcine type Alkaloids.
- Demecolcine type Chemical114806838.
- Demecolcine type Compound114818238.
- Demecolcine type Element114840755.
- Demecolcine type Ketone114926294.
- Demecolcine type Ketones.
- Demecolcine type Material114580897.
- Demecolcine type Matter100020827.
- Demecolcine type OrganicCompound114727670.
- Demecolcine type Part113809207.
- Demecolcine type PhenolEthers.
- Demecolcine type PhysicalEntity100001930.
- Demecolcine type Quintessence114847103.
- Demecolcine type Relation100031921.
- Demecolcine type Substance100019613.
- Demecolcine type Drug.
- Demecolcine type DrugProduct.
- Demecolcine type FunctionalSubstance.
- Demecolcine comment "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic.".
- Demecolcine label "Demecolcine".
- Demecolcine sameAs m.04zwrkt.
- Demecolcine sameAs Q16959658.
- Demecolcine sameAs Q16959658.
- Demecolcine sameAs Demecolcine.
- Demecolcine wasDerivedFrom Demecolcine?oldid=567923123.
- Demecolcine depiction Demecolcine.png.
- Demecolcine isPrimaryTopicOf Demecolcine.
