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- Denufosol abstract "Denufosol (INN) is an inhaled drug for the treatment of cystic fibrosis, being developed by Inspire Pharmaceuticals and sponsored by the Cystic Fibrosis Foundation. It was tested in two Phase III clinical trials, TIGER-1 and TIGER-2. Initially, in the first Phase III trial, TIGER-1, the compound showed significant results as compared with placebo. In the second Phase III trial, TIGER-2, the compound did not meet the primary endpoint, a significant change in baseline FEV1 (forced expiratory volume in one second) at the week 48 endpoint as compared to placebo. As of 2011, no additional clinical studies are being conducted with the compound. The drug was also investigated for the treatment of retinal detachment and other retinal diseases, but trials were terminated in 2006.".
- Denufosol atcPrefix "none".
- Denufosol casNumber "211448-85-0".
- Denufosol fdaUniiCode "5PC250KSSH".
- Denufosol iupacName "(3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate".
- Denufosol pubchem "192708".
- Denufosol thumbnail Denufosol.svg?width=300.
- Denufosol wikiPageID "31375957".
- Denufosol wikiPageRevisionID "546132912".
- Denufosol alt "Denufosol tetrasodium".
- Denufosol atcPrefix "none".
- Denufosol c "18".
- Denufosol casNumber "211448".
- Denufosol h "27".
- Denufosol hasPhotoCollection Denufosol.
- Denufosol iupacName "(3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate".
- Denufosol legalStatus "Investigational".
- Denufosol molecularWeight "773.32".
- Denufosol n "5".
- Denufosol o "21".
- Denufosol p "4".
- Denufosol pubchem "192708".
- Denufosol routesOfAdministration Inhalation.
- Denufosol smiles "C1CO".
- Denufosol synonyms "2".
- Denufosol synonyms "INS37217".
- Denufosol unii "5".
- Denufosol verifiedrevid "451607985".
- Denufosol width "300".
- Denufosol subject Category:Drugs_acting_on_the_respiratory_system.
- Denufosol subject Category:Nucleotides.
- Denufosol type Abstraction100002137.
- Denufosol type Chemical114806838.
- Denufosol type Compound114818238.
- Denufosol type Ester114850483.
- Denufosol type Material114580897.
- Denufosol type Matter100020827.
- Denufosol type Nucleotide114964590.
- Denufosol type Nucleotides.
- Denufosol type OrganicCompound114727670.
- Denufosol type Part113809207.
- Denufosol type PhysicalEntity100001930.
- Denufosol type Relation100031921.
- Denufosol type Substance100019613.
- Denufosol type Drug.
- Denufosol type FunctionalSubstance.
- Denufosol comment "Denufosol (INN) is an inhaled drug for the treatment of cystic fibrosis, being developed by Inspire Pharmaceuticals and sponsored by the Cystic Fibrosis Foundation. It was tested in two Phase III clinical trials, TIGER-1 and TIGER-2. Initially, in the first Phase III trial, TIGER-1, the compound showed significant results as compared with placebo.".
- Denufosol label "Denufosol".
- Denufosol label "Denufosol".
- Denufosol sameAs Denufosol.
- Denufosol sameAs Denufosol.
- Denufosol sameAs m.0gkzlrg.
- Denufosol sameAs Q908026.
- Denufosol sameAs Q908026.
- Denufosol sameAs Denufosol.
- Denufosol wasDerivedFrom Denufosol?oldid=546132912.
- Denufosol depiction Denufosol.svg.
- Denufosol isPrimaryTopicOf Denufosol.
