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- Dermorphin abstract "Dermorphin is a hepta-peptide first isolated from the skin of South American frogs belonging to the genus Phyllomedusa. The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors. Dermorphin is about 30–40 times more potent than morphine but theoretically may be less likely to produce drug tolerance and addiction (due to its high potency). The amino acid sequence of dermorphin is H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2.Dermorphin is not found in humans or other mammals and similar D-amino acid peptides have only been found in bacteria, amphibians and molluscs. Dermorphin appears to be made in these through an unusual posttranslational modification carried out by an amino acid isomerase. This unusual process is needed because the D-alanine in this peptide is not among the 20 amino acids coded for in the genetic code and thus the peptide cannot be synthesized in the usual way from the encodings in the genome of an organism.".
- Dermorphin thumbnail Dermorphin.svg?width=300.
- Dermorphin wikiPageID "1540000".
- Dermorphin wikiPageRevisionID "602344483".
- Dermorphin hasPhotoCollection Dermorphin.
- Dermorphin imagefile "dermorphin.svg".
- Dermorphin imagesize "200".
- Dermorphin othernames "Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide".
- Dermorphin verifiedfields "changed".
- Dermorphin verifiedrevid "413081297".
- Dermorphin watchedfields "changed".
- Dermorphin subject Category:Mu-opioid_agonists.
- Dermorphin subject Category:Opioid_peptides.
- Dermorphin type Abstraction100002137.
- Dermorphin type Amide114724264.
- Dermorphin type Chemical114806838.
- Dermorphin type Compound114818238.
- Dermorphin type Material114580897.
- Dermorphin type Matter100020827.
- Dermorphin type OrganicCompound114727670.
- Dermorphin type Part113809207.
- Dermorphin type Peptide114743046.
- Dermorphin type Peptides.
- Dermorphin type PhysicalEntity100001930.
- Dermorphin type Relation100031921.
- Dermorphin type Substance100019613.
- Dermorphin type ChemicalCompound.
- Dermorphin type ChemicalSubstance.
- Dermorphin type ChemicalObject.
- Dermorphin type Thing.
- Dermorphin comment "Dermorphin is a hepta-peptide first isolated from the skin of South American frogs belonging to the genus Phyllomedusa. The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors. Dermorphin is about 30–40 times more potent than morphine but theoretically may be less likely to produce drug tolerance and addiction (due to its high potency).".
- Dermorphin label "Dermorfina".
- Dermorphin label "Dermorphin".
- Dermorphin label "デルモルフィン".
- Dermorphin sameAs Dermorfina.
- Dermorphin sameAs デルモルフィン.
- Dermorphin sameAs m.058zb_.
- Dermorphin sameAs Q1771654.
- Dermorphin sameAs Q1771654.
- Dermorphin sameAs Dermorphin.
- Dermorphin wasDerivedFrom Dermorphin?oldid=602344483.
- Dermorphin depiction Dermorphin.svg.
- Dermorphin isPrimaryTopicOf Dermorphin.