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- Desflurane abstract "Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Like halothane, enflurane and isoflurane and Sevoflurane, it is a racemic mixture of (R) and (S) optical isomers (enantiomers). Together with sevoflurane, it is gradually replacing isoflurane for human use, except in the third world, where its high cost precludes its use. It has the most rapid onset and offset of the volatile anesthetic drugs used for general anesthesia due to its low solubility in blood.Some drawbacks of desflurane are its low potency, its pungency and its high cost. It may cause tachycardia and airway irritability when administered at concentrations greater than 10 vol%. Due to this airway irritability, desflurane is infrequently used to induce anesthesia via inhalation techniques.Though it vaporises very readily, it is a liquid at room temperature. Anaesthetic machines are fitted with a specialized anaesthetic vaporiser unit that heats liquid desflurane to a constant temperature. This enables the agent to be available at a constant vapor pressure, negating the effects fluctuating ambient temperatures would otherwise have on its concentration imparted into the fresh gas flow of the anesthesia machine.Desflurane, along with enflurane and to a lesser extent isoflurane, has been shown to react with the carbon dioxide absorbent in anesthesia circuits to produce detectable levels of carbon monoxide through degradation of the anesthetic agent. The CO2 absorbent, Baralyme, when dried, is most culpable for the production of carbon monoxide from desflurane degradation, although it is also seen with soda lime absorbent as well. Dry conditions in the carbon dioxide absorbent are conducive to this phenomenon, such as those resulting from high fresh gas flows.".
- Desflurane atcPrefix "N01".
- Desflurane atcSuffix "AB07".
- Desflurane casNumber "57041-67-5".
- Desflurane chEBI "4445".
- Desflurane drugbank "DB01189".
- Desflurane fdaUniiCode "CRS35BZ94Q".
- Desflurane iupacName "2-(difluoromethoxy)-1,1,1,2-tetrafluoro-ethane".
- Desflurane pubchem "42113".
- Desflurane thumbnail Desflurane2.svg?width=300.
- Desflurane wikiPageExternalLink dokserv?idn=977851818&dok_var=d1&dok_ext=pdf&filename=977851818.pdf.
- Desflurane wikiPageExternalLink diss.pdf.
- Desflurane wikiPageID "668634".
- Desflurane wikiPageRevisionID "604165361".
- Desflurane atcPrefix "N01".
- Desflurane atcSuffix "AB07".
- Desflurane c "3".
- Desflurane casNumber "57041".
- Desflurane chebi "4445".
- Desflurane chembl "1200733".
- Desflurane chemspiderid "38403".
- Desflurane drugbank "DB01189".
- Desflurane eliminationHalfLife "Elimination dependent on minute ventilation".
- Desflurane f "6".
- Desflurane h "2".
- Desflurane hasPhotoCollection Desflurane.
- Desflurane image "Desflurane-3D-balls.png".
- Desflurane inchi "1".
- Desflurane inchikey "DPYMFVXJLLWWEU-UHFFFAOYAB".
- Desflurane iupacName "2".
- Desflurane kegg "D00546".
- Desflurane metabolism "Not metabolized".
- Desflurane molecularWeight "168.038".
- Desflurane o "1".
- Desflurane pubchem "42113".
- Desflurane smiles "FCCOCF".
- Desflurane stdinchi "1".
- Desflurane stdinchikey "DPYMFVXJLLWWEU-UHFFFAOYSA-N".
- Desflurane unii "CRS35BZ94Q".
- Desflurane verifiedfields "changed".
- Desflurane verifiedrevid "460777556".
- Desflurane subject Category:Ethers.
- Desflurane subject Category:General_anesthetics.
- Desflurane subject Category:Organofluorides.
- Desflurane type Abstraction100002137.
- Desflurane type Element114840755.
- Desflurane type Ethers.
- Desflurane type Matter100020827.
- Desflurane type Part113809207.
- Desflurane type PhysicalEntity100001930.
- Desflurane type Quintessence114847103.
- Desflurane type Relation100031921.
- Desflurane type Substance100019613.
- Desflurane type Drug.
- Desflurane type DrugProduct.
- Desflurane type FunctionalSubstance.
- Desflurane comment "Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Like halothane, enflurane and isoflurane and Sevoflurane, it is a racemic mixture of (R) and (S) optical isomers (enantiomers). Together with sevoflurane, it is gradually replacing isoflurane for human use, except in the third world, where its high cost precludes its use.".
- Desflurane label "Desfluraan".
- Desflurane label "Desfluran".
- Desflurane label "Desfluran".
- Desflurane label "Desflurane".
- Desflurane label "Desflurane".
- Desflurane label "Desflurano".
- Desflurane label "Desflurano".
- Desflurane label "Desflurano".
- Desflurane sameAs Desfluran.
- Desflurane sameAs Desflurano.
- Desflurane sameAs Desflurane.
- Desflurane sameAs Desflurano.
- Desflurane sameAs Desfluraan.
- Desflurane sameAs Desfluran.
- Desflurane sameAs Desflurano.
- Desflurane sameAs m.031bg3.
- Desflurane sameAs Q419383.
- Desflurane sameAs Q419383.
- Desflurane sameAs desflurane.
- Desflurane sameAs DB01189.
- Desflurane sameAs 42113.
- Desflurane sameAs Desflurane.
- Desflurane wasDerivedFrom Desflurane?oldid=604165361.
- Desflurane depiction Desflurane2.svg.
- Desflurane isPrimaryTopicOf Desflurane.
