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- Devazepide abstract "Devazepide (L-364,718, MK-329) is a drug which is structurally derived from the benzodiazepine family, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as a cholecystokinin antagonist selective for the CCKA subtype. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCKA receptor. Evans, B. E.; Rittle, K. E.; DiPardo, R. M.; Freidinger, R. M.; Whitter,W. L.; People,W. T.;Lendell, G. F.; Veber, D. F.; Anderson, P. S.; Chang, R. S. L.; Lotti, V. J.; Cerino, D. J.;Chen, T. B.; Kling, P. J.; Kunkel, K. A.; Springer, J. P.; Hirschfield, J.; J. Med. Chem.1988, 31, 2235.http://dx.doi.org/10.1021/jm00120a002".
- Devazepide atcPrefix "none".
- Devazepide casNumber "103420-77-5".
- Devazepide fdaUniiCode "JE6P7QY7NH".
- Devazepide iupacName "N-(1-methyl- 2-oxo- 5-phenyl- 3H-1,4-benzodiazepin-3-yl)- 1H-indole -2-carboxamide".
- Devazepide pubchem "443375".
- Devazepide thumbnail Devazepide.png?width=300.
- Devazepide wikiPageExternalLink jm00120a002.
- Devazepide wikiPageID "20252095".
- Devazepide wikiPageRevisionID "586898063".
- Devazepide atcPrefix "none".
- Devazepide c "25".
- Devazepide casNumber "103420".
- Devazepide chembl "9506".
- Devazepide chemspiderid "391607".
- Devazepide h "20".
- Devazepide hasPhotoCollection Devazepide.
- Devazepide inchi "1".
- Devazepide inchikey "NFHRQQKPEBFUJK-HSZRJFAPBU".
- Devazepide iupacName "N-- 1H-indole -2-carboxamide".
- Devazepide iupharLigand "878".
- Devazepide kegg "D02693".
- Devazepide molecularWeight "408.452".
- Devazepide n "4".
- Devazepide o "2".
- Devazepide pubchem "443375".
- Devazepide smiles "O=CN[C@H]3/N=Cc5ccccc5".
- Devazepide stdinchi "1".
- Devazepide stdinchikey "NFHRQQKPEBFUJK-HSZRJFAPSA-N".
- Devazepide unii "JE6P7QY7NH".
- Devazepide verifiedfields "changed".
- Devazepide verifiedrevid "405810511".
- Devazepide watchedfields "changed".
- Devazepide subject Category:Amides.
- Devazepide subject Category:Cholecystokinin_antagonists.
- Devazepide subject Category:Indoles.
- Devazepide type Adversary109773245.
- Devazepide type CausalAgent100007347.
- Devazepide type CholecystokininAntagonists.
- Devazepide type LivingThing100004258.
- Devazepide type Object100002684.
- Devazepide type Organism100004475.
- Devazepide type Person100007846.
- Devazepide type PhysicalEntity100001930.
- Devazepide type Whole100003553.
- Devazepide type YagoLegalActor.
- Devazepide type YagoLegalActorGeo.
- Devazepide type Drug.
- Devazepide type DrugProduct.
- Devazepide type FunctionalSubstance.
- Devazepide comment "Devazepide (L-364,718, MK-329) is a drug which is structurally derived from the benzodiazepine family, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as a cholecystokinin antagonist selective for the CCKA subtype. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux.".
- Devazepide label "Devazepide".
- Devazepide sameAs m.04zw2zt.
- Devazepide sameAs Q5266620.
- Devazepide sameAs Q5266620.
- Devazepide sameAs Devazepide.
- Devazepide wasDerivedFrom Devazepide?oldid=586898063.
- Devazepide depiction Devazepide.png.
- Devazepide isPrimaryTopicOf Devazepide.
