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- Dipeptidase_1 abstract "Dipeptidase 1 is an enzyme that in humans is encoded by the DPEP1 gene.DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990).[supplied by OMIM]".
- Dipeptidase_1 entrezgene "1800".
- Dipeptidase_1 wikiPageID "14817129".
- Dipeptidase_1 wikiPageRevisionID "591018961".
- Dipeptidase_1 hasPhotoCollection Dipeptidase_1.
- Dipeptidase_1 requireManualInspection "no".
- Dipeptidase_1 summaryText "DPEP1 is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 . DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem . Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells .[supplied by OMIM]".
- Dipeptidase_1 updateCitations "yes".
- Dipeptidase_1 updatePage "yes".
- Dipeptidase_1 updateProteinBox "yes".
- Dipeptidase_1 updateSummary "yes".
- Dipeptidase_1 type Biomolecule.
- Dipeptidase_1 type Protein.
- Dipeptidase_1 type BiologicalObject.
- Dipeptidase_1 comment "Dipeptidase 1 is an enzyme that in humans is encoded by the DPEP1 gene.DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984).".
- Dipeptidase_1 label "Dipeptidase 1".
- Dipeptidase_1 sameAs m.03gyz02.
- Dipeptidase_1 sameAs Q5279726.
- Dipeptidase_1 sameAs Q5279726.
- Dipeptidase_1 sameAs 2016.
- Dipeptidase_1 wasDerivedFrom Dipeptidase_1?oldid=591018961.
- Dipeptidase_1 isPrimaryTopicOf Dipeptidase_1.