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- Dispersin_B abstract "Dispersin B (also known as DspB or DispersinB) is a 40 kDa glycoside hydrolase produced by the periodontal pathogen, Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony by disrupting biofilm formation. The enzyme catalyzes the hydrolysis of linear polymers of N-acetyl-D-glucosamines found in the biofilm matrices. Poly-acetyl glucosamines are integral to the structural integrity of the biofilms of various Gram-positive bacteria and Gram-negative bacteria and are referred to as PIA (PNAG,PS/A) in Staphylococcus species and PGA in Escherichia coli. By degrading the biofilm matrix, Dispersin B allows for the release of bacterial cells that can adhere to new surfaces close by and extend the biofilm or start new colonies. Currently there is interest in Dispersin B as a commercial anti-biofilm agent that could be combined with antibiotics for the treatment of bacterial infections.".
- Dispersin_B ecNumber "3.2.1.52".
- Dispersin_B thumbnail DispB.jpeg?width=300.
- Dispersin_B wikiPageExternalLink dispersinb.htm.
- Dispersin_B wikiPageID "20834652".
- Dispersin_B wikiPageRevisionID "597615628".
- Dispersin_B caption "Ribbon diagram of Dispersin B".
- Dispersin_B ecNumber "3.2".
- Dispersin_B ecnumber "3.2".
- Dispersin_B hasPhotoCollection Dispersin_B.
- Dispersin_B name "Dispersin B".
- Dispersin_B pdb "1".
- Dispersin_B refseq "YP_001449721".
- Dispersin_B symbol "DspB".
- Dispersin_B uniprot "Q840G9".
- Dispersin_B width "250".
- Dispersin_B subject Category:EC_3.2.1.
- Dispersin_B type Biomolecule.
- Dispersin_B type Enzyme.
- Dispersin_B type ProteinMolecule.
- Dispersin_B type BiologicalObject.
- Dispersin_B comment "Dispersin B (also known as DspB or DispersinB) is a 40 kDa glycoside hydrolase produced by the periodontal pathogen, Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony by disrupting biofilm formation. The enzyme catalyzes the hydrolysis of linear polymers of N-acetyl-D-glucosamines found in the biofilm matrices.".
- Dispersin_B label "Dispersin B".
- Dispersin_B sameAs m.055g_wp.
- Dispersin_B sameAs Q5282577.
- Dispersin_B sameAs Q5282577.
- Dispersin_B wasDerivedFrom Dispersin_B?oldid=597615628.
- Dispersin_B depiction DispB.jpeg.
- Dispersin_B isPrimaryTopicOf Dispersin_B.
- Dispersin_B name "Dispersin B".
