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- Draize_test abstract "The Draize Test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5mL or 0.5g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for set amount of time before rinsing it out and recording its effects. The animals are observed for up to 14 days for signs of erythema and edema in the skin test, and redness, swelling, discharge, ulceration, hemorrhaging, cloudiness, or blindness in the tested eye. The test subject is commonly an albino rabbit, though other species are used too, including dogs. The animals are euthanized after testing if the test renders irreversible damage to the eye or skin. Animals may be re-used for testing purposes if the product tested causes no permanent damage. Animals are typically reused after a "wash out" period during which all traces of the tested product are allowed to disperse from the test site.The tests are controversial. They are viewed as cruel as well as unscientific by critics because of the differences between rabbit and human eyes, and the subjective nature of the visual evaluations. The FDA supports the test, stating that "to date, no single test, or battery of tests, has been accepted by the scientific community as a replacement [for] ... the Draize test" Because of its controversial nature, the use of the Draize test in the U.S. and Europe has declined in recent years and is sometimes modified so that anaesthetics are administered and lower doses of the test substances used. Chemicals already shown to have adverse effects in vitro are not currently used in a Draize test, thereby reducing the number and severity of tests carried out.".
- Draize_test thumbnail DraizeTest-PETA.jpg?width=300.
- Draize_test wikiPageID "184182".
- Draize_test wikiPageRevisionID "591063255".
- Draize_test hasPhotoCollection Draize_test.
- Draize_test subject Category:Animal_rights.
- Draize_test subject Category:Animal_testing.
- Draize_test subject Category:Toxicology_tests.
- Draize_test type Abstraction100002137.
- Draize_test type Abstraction105854150.
- Draize_test type AnimalRights.
- Draize_test type Cognition100023271.
- Draize_test type Concept105835747.
- Draize_test type Content105809192.
- Draize_test type Experiment105798043.
- Draize_test type HigherCognitiveProcess105770664.
- Draize_test type Idea105833840.
- Draize_test type Inquiry105797597.
- Draize_test type ProblemSolving105796750.
- Draize_test type Process105701363.
- Draize_test type PsychologicalFeature100023100.
- Draize_test type Right105174653.
- Draize_test type Thinking105770926.
- Draize_test type ToxicologyTests.
- Draize_test type Trial105799212.
- Draize_test comment "The Draize Test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5mL or 0.5g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for set amount of time before rinsing it out and recording its effects.".
- Draize_test label "Draize test".
- Draize_test label "Draize-Test".
- Draize_test label "Draize-test".
- Draize_test label "Test Draize'a".
- Draize_test label "ドレイズ試験".
- Draize_test sameAs Draize-Test.
- Draize_test sameAs ドレイズ試験.
- Draize_test sameAs Draize-test.
- Draize_test sameAs Test_Draize'a.
- Draize_test sameAs m.019511.
- Draize_test sameAs Q1255511.
- Draize_test sameAs Q1255511.
- Draize_test sameAs Draize_test.
- Draize_test wasDerivedFrom Draize_test?oldid=591063255.
- Draize_test depiction DraizeTest-PETA.jpg.
- Draize_test isPrimaryTopicOf Draize_test.
