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- EIF4EBP1 abstract "Eukaryotic translation initiation factor 4E-binding protein 1 is a protein that in humans is encoded by the EIF4EBP1 gene.This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.".
- EIF4EBP1 entrezgene "1978".
- EIF4EBP1 wikiPageID "14129846".
- EIF4EBP1 wikiPageRevisionID "601770536".
- EIF4EBP1 hasPhotoCollection EIF4EBP1.
- EIF4EBP1 requireManualInspection "no".
- EIF4EBP1 summaryText "This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.".
- EIF4EBP1 updateCitations "yes".
- EIF4EBP1 updatePage "yes".
- EIF4EBP1 updateProteinBox "yes".
- EIF4EBP1 updateSummary "yes".
- EIF4EBP1 type Biomolecule.
- EIF4EBP1 type Protein.
- EIF4EBP1 type BiologicalObject.
- EIF4EBP1 comment "Eukaryotic translation initiation factor 4E-binding protein 1 is a protein that in humans is encoded by the EIF4EBP1 gene.This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation.".
- EIF4EBP1 label "4E-BP".
- EIF4EBP1 label "EIF4EBP1".
- EIF4EBP1 sameAs 4E-BP.
- EIF4EBP1 sameAs m.03cvh4f.
- EIF4EBP1 sameAs Q5323183.
- EIF4EBP1 sameAs Q5323183.
- EIF4EBP1 wasDerivedFrom EIF4EBP1?oldid=601770536.
- EIF4EBP1 isPrimaryTopicOf EIF4EBP1.