Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ESM1> ?p ?o. }
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- ESM1 abstract "Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene.This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals.. The ESM-1 gene product is also called endocan since 2001, when it was characterized as a dermatan sulfate proteoglycan by Bechard et al.Recently, endocan / ESM-1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Endocan expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF (vascular endothelial growth factor) or FGF-2 (fibroblast growth factor 2).In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against endocan / ESM-1.".
- ESM1 entrezgene "11082".
- ESM1 wikiPageID "15067998".
- ESM1 wikiPageRevisionID "591230434".
- ESM1 hasPhotoCollection ESM1.
- ESM1 requireManualInspection "no".
- ESM1 summaryText "This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals.".
- ESM1 updateCitations "yes".
- ESM1 updatePage "yes".
- ESM1 updateProteinBox "yes".
- ESM1 updateSummary "yes".
- ESM1 type Biomolecule.
- ESM1 type Protein.
- ESM1 type BiologicalObject.
- ESM1 comment "Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene.This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals..".
- ESM1 label "ESM1".
- ESM1 sameAs m.03hgfwh.
- ESM1 sameAs Q5324179.
- ESM1 sameAs Q5324179.
- ESM1 wasDerivedFrom ESM1?oldid=591230434.
- ESM1 isPrimaryTopicOf ESM1.