Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Ecotin> ?p ?o. }
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- Ecotin abstract "In molecular biology, ecotin is a protease inhibitor which belongs to MEROPS inhibitor family I11, clan IN. Ecotins are dimeric periplasmic proteins from Escherichia coli and related Gram-negative bacteria that have been shown to be potent inhibitors of many trypsin-fold serine proteases of widely varying substrate specificity, which belong to MEROPS peptidase family S1. Phylogenetic analysis suggested that ecotin has an exogenous target, possibly neutrophil elastase. Ecotin from E. coli, Yersinia pestis, and Pseudomonas aeruginosa, all species that encounter the mammalian immune system, inhibit neutrophil elastase strongly while ecotin from the plant pathogen Pantoea citrea inhibits neutrophil elastase 1000-fold less potently. Ecotins all potently inhibit pancreatic digestive peptidases trypsin and chymotrypsin, while showing more variable inhibition of the blood peptidases Factor Xa, thrombin, and urokinase-type plasminogen activator.".
- Ecotin symbol "Ecotin".
- Ecotin thumbnail PDB_1ifg_EBI.jpg?width=300.
- Ecotin wikiPageExternalLink famsum?family=S1.
- Ecotin wikiPageExternalLink pepsum?id=I11.001;type=I.
- Ecotin wikiPageID "32646106".
- Ecotin wikiPageRevisionID "591143597".
- Ecotin caption "crystal structure of a monomeric form of general protease inhibitor, ecotin in absence of a protease".
- Ecotin hasPhotoCollection Ecotin.
- Ecotin interpro "IPR005658".
- Ecotin name "Ecotin".
- Ecotin pfam "PF03974".
- Ecotin scop "1".
- Ecotin symbol "Ecotin".
- Ecotin subject Category:Protein_families.
- Ecotin type Abstraction100002137.
- Ecotin type Family108078020.
- Ecotin type Group100031264.
- Ecotin type Organization108008335.
- Ecotin type ProteinFamilies.
- Ecotin type SocialGroup107950920.
- Ecotin type Unit108189659.
- Ecotin type YagoLegalActor.
- Ecotin type YagoLegalActorGeo.
- Ecotin type YagoPermanentlyLocatedEntity.
- Ecotin type Biomolecule.
- Ecotin type Protein.
- Ecotin type BiologicalObject.
- Ecotin comment "In molecular biology, ecotin is a protease inhibitor which belongs to MEROPS inhibitor family I11, clan IN. Ecotins are dimeric periplasmic proteins from Escherichia coli and related Gram-negative bacteria that have been shown to be potent inhibitors of many trypsin-fold serine proteases of widely varying substrate specificity, which belong to MEROPS peptidase family S1. Phylogenetic analysis suggested that ecotin has an exogenous target, possibly neutrophil elastase. Ecotin from E.".
- Ecotin label "Ecotin".
- Ecotin sameAs m.0h3ppl4.
- Ecotin sameAs Q5333890.
- Ecotin sameAs Q5333890.
- Ecotin sameAs Ecotin.
- Ecotin wasDerivedFrom Ecotin?oldid=591143597.
- Ecotin depiction PDB_1ifg_EBI.jpg.
- Ecotin isPrimaryTopicOf Ecotin.
