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- phosphodiesterase_1 abstract "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 is an enzyme that in humans is encoded by the ENPP1 gene.This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with Idiopathic infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.".
- phosphodiesterase_1 entrezgene "5167".
- phosphodiesterase_1 wikiPageID "14725817".
- phosphodiesterase_1 wikiPageRevisionID "591144012".
- phosphodiesterase_1 hasPhotoCollection phosphodiesterase_1.
- phosphodiesterase_1 requireManualInspection "no".
- phosphodiesterase_1 summaryText "This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with Idiopathic infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine , and insulin resistance.".
- phosphodiesterase_1 updateCitations "yes".
- phosphodiesterase_1 updatePage "yes".
- phosphodiesterase_1 updateProteinBox "yes".
- phosphodiesterase_1 updateSummary "yes".
- phosphodiesterase_1 type Biomolecule.
- phosphodiesterase_1 type Protein.
- phosphodiesterase_1 type BiologicalObject.
- phosphodiesterase_1 comment "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 is an enzyme that in humans is encoded by the ENPP1 gene.This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits.".
- phosphodiesterase_1 label "Ectonucleotide pyrophosphatase/phosphodiesterase 1".
- phosphodiesterase_1 label "Nukleotid-Diphosphatase".
- phosphodiesterase_1 sameAs Nukleotid-Diphosphatase.
- phosphodiesterase_1 sameAs m.03gvpcd.
- phosphodiesterase_1 sameAs Q2004578.
- phosphodiesterase_1 sameAs Q2004578.
- phosphodiesterase_1 sameAs ENPP1.
- phosphodiesterase_1 sameAs 508.
- phosphodiesterase_1 wasDerivedFrom phosphodiesterase_1?oldid=591144012.
- phosphodiesterase_1 isPrimaryTopicOf phosphodiesterase_1.