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- efavirenz abstract "Emtricitabine/tenofovir/efavirenz (INNs, trade names Atripla ®, Viraday ®) is a fixed-dose combination drug for the treatment of HIV infection. It combines Gilead Sciences's tenofovir and emtricitabine (already available in the anti-HIV combination Truvada ®) with Merck & Co's efavirenz into a fixed-dose pill. Combining the three drugs into a single, once-daily pill reduces pill burden and simplifies dosing schedules, and therefore has the potential to increase adherence to antiretroviral therapy.Atripla is the first multi-class antiretroviral drug available in the United States and represents the first collaboration between two U.S. pharmaceutical companies to combine their patented anti-HIV drugs into one product. The drug retails in the United States for US$1,850 for a one-month supply. An equivalent two pill regimen is available in developing countries at a price of about US$1.00 per day, as Gilead Sciences has licensed the patents covering emtricitabine/tenofovir to the Medicines Patent Pool and Merck and Co makes efavirenz available in developing countries at a reduced price. It was approved by the U.S. FDA on July 12, 2006. In the UK, the drug cost to the NHS is GB£626.90 per month as of March 2012.Atripla is a fixed dose combination of 600 mg efavirenz, 300 mg tenofovir, and 200 mg emtricitabine. In adults, it is taken once daily on an empty stomach. Dosing at bedtime is recommended to improve tolerability of nervous system symptoms. Atripla is not recommended for patients under 18 years of age.Atripla is a pink, film-coated tablet with "123" impressed on one side.In North America and Europe, Atripla is marketed jointly by Gilead Sciences and Bristol-Myers Squibb, but in much of the developing world, marketing and distribution is handled by Merck & Co. Cipla released its own version of Atripla in India, called Viraday. In Argentina, Atripla is marketed by Laboratorios Gador.In South Africa, the National Minister of Health, Doctor Aaron Motsoaledi, administered to the first state patient a fixed dose combination (FDC) tablet of Emtricitabine/Tenofovir/Efavirenz on 9 April 2013 in GaRankuwa.".
- efavirenz atcPrefix "J05".
- efavirenz atcSuffix "AR06".
- efavirenz casNumber "731772-50-2".
- efavirenz wikiPageExternalLink atripla.com.
- efavirenz wikiPageExternalLink atripla.html.
- efavirenz wikiPageID "5940556".
- efavirenz wikiPageRevisionID "593584873".
- efavirenz atcPrefix "J05".
- efavirenz atcSuffix "AR06".
- efavirenz casNumber "731772".
- efavirenz class Nucleoside.
- efavirenz class Reverse-transcriptase_inhibitor.
- efavirenz class "Nucleotide analogue reverse transcriptase inhibitor".
- efavirenz component "Efavirenz".
- efavirenz component "Emtricitabine".
- efavirenz component "Tenofovir disoproxil fumarate".
- efavirenz hasPhotoCollection efavirenz.
- efavirenz legalUk "POM".
- efavirenz legalUs "Rx-only".
- efavirenz niaidChemdb "26223".
- efavirenz pregnancyUs "D".
- efavirenz routesOfAdministration "Oral".
- efavirenz type "combo".
- efavirenz verifiedrevid "447573543".
- efavirenz subject Category:Bristol-Myers_Squibb.
- efavirenz subject Category:Fixed_dose_combination_(antiretroviral).
- efavirenz subject Category:Gilead_Sciences.
- efavirenz subject Category:World_Health_Organization_essential_medicines.
- efavirenz type Abstraction100002137.
- efavirenz type Cognition100023271.
- efavirenz type Content105809192.
- efavirenz type Discipline105996646.
- efavirenz type KnowledgeDomain105999266.
- efavirenz type LifeScience106037298.
- efavirenz type MedicalScience106045562.
- efavirenz type Medicine106043075.
- efavirenz type NaturalScience106000400.
- efavirenz type PsychologicalFeature100023100.
- efavirenz type Science105999797.
- efavirenz type WorldHealthOrganizationEssentialMedicines.
- efavirenz type Drug.
- efavirenz type FunctionalSubstance.
- efavirenz comment "Emtricitabine/tenofovir/efavirenz (INNs, trade names Atripla ®, Viraday ®) is a fixed-dose combination drug for the treatment of HIV infection. It combines Gilead Sciences's tenofovir and emtricitabine (already available in the anti-HIV combination Truvada ®) with Merck & Co's efavirenz into a fixed-dose pill.".
- efavirenz label "Efavirenz/emtricitabine/ténofovir".
- efavirenz label "Emtricitabine/tenofovir/efavirenz".
- efavirenz sameAs ténofovir.
- efavirenz sameAs m.0ffmvx.
- efavirenz sameAs Q2869808.
- efavirenz sameAs Q2869808.
- efavirenz sameAs efavirenz.
- efavirenz wasDerivedFrom efavirenz?oldid=593584873.
- efavirenz isPrimaryTopicOf efavirenz.