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- Epigenetics abstract "In biology, and specifically genetics, epigenetics is the study of heritable changes in gene activity that are not caused by changes in the DNA sequence; it also can be used to describe the study of stable, long-term alterations in the transcriptional potential of a cell that are not necessarily heritable. Unlike simple genetics based on changes to the DNA sequence (the genotype), the changes in gene expression or cellular phenotype of epigenetics have other causes, thus use of the term epi- (Greek: επί- over, outside of, around) -genetics.The term also refers to the changes themselves: functionally relevant changes to the genome that do not involve a change in the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA. These epigenetic changes may last through cell divisions for the duration of the cell's life, and may also last for multiple generations even though they do not involve changes in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism's genes to behave (or "express themselves") differently. (There are objections to the use of the term epigenetic to describe chemical modification of histone, since it remains unclear whether or not histone modifications are heritable.)One example of an epigenetic change in eukaryotic biology is the process of cellular differentiation. During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells. In other words, as a single fertilized egg cell – the zygote – continues to divide, the resulting daughter cells change into all the different cell types in an organism, including neurons, muscle cells, epithelium, endothelium of blood vessels, etc., by activating some genes while inhibiting the expression of others.In 2011, it was demonstrated that the methylation of mRNA plays a critical role in human energy homeostasis. The obesity-associated FTO gene is shown to be able to demethylate N6-methyladenosine in RNA. This discovery launched the subfield of RNA epigenetics.".
- Epigenetics thumbnail Epigenetic_mechanisms.jpg?width=300.
- Epigenetics wikiPageExternalLink cover.
- Epigenetics wikiPageExternalLink doc_WTX036556.html.
- Epigenetics wikiPageExternalLink ghostgenes.shtml.
- Epigenetics wikiPageExternalLink index.php.
- Epigenetics wikiPageExternalLink www.epigenome.eu.
- Epigenetics wikiPageExternalLink www.epigenome.org.
- Epigenetics wikiPageExternalLink www.epigenomes.ca.
- Epigenetics wikiPageExternalLink epigenetics.htm.
- Epigenetics wikiPageID "49033".
- Epigenetics wikiPageRevisionID "604586479".
- Epigenetics hasPhotoCollection Epigenetics.
- Epigenetics subject Category:Epigenetics.
- Epigenetics subject Category:Genetic_mapping.
- Epigenetics comment "In biology, and specifically genetics, epigenetics is the study of heritable changes in gene activity that are not caused by changes in the DNA sequence; it also can be used to describe the study of stable, long-term alterations in the transcriptional potential of a cell that are not necessarily heritable.".
- Epigenetics label "Epigenetica".
- Epigenetics label "Epigenetica".
- Epigenetics label "Epigenetics".
- Epigenetics label "Epigenetik".
- Epigenetics label "Epigenetyka".
- Epigenetics label "Epigenética".
- Epigenetics label "Epigenética".
- Epigenetics label "Épigénétique".
- Epigenetics label "Эпигенетика".
- Epigenetics label "علم الوراثة اللاجيني".
- Epigenetics label "エピジェネティクス".
- Epigenetics label "表觀遺傳學".
- Epigenetics sameAs Epigenetika.
- Epigenetics sameAs Epigenetik.
- Epigenetics sameAs Epigenética.
- Epigenetics sameAs Epigenetika.
- Epigenetics sameAs Épigénétique.
- Epigenetics sameAs Epigenetika.
- Epigenetics sameAs Epigenetica.
- Epigenetics sameAs エピジェネティクス.
- Epigenetics sameAs 후성유전학.
- Epigenetics sameAs Epigenetica.
- Epigenetics sameAs Epigenetyka.
- Epigenetics sameAs Epigenética.
- Epigenetics sameAs m.0d2l9.
- Epigenetics sameAs Q26939.
- Epigenetics sameAs Q26939.
- Epigenetics wasDerivedFrom Epigenetics?oldid=604586479.
- Epigenetics depiction Epigenetic_mechanisms.jpg.
- Epigenetics isPrimaryTopicOf Epigenetics.
