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Epoxide_hydrolase abstract "Epoxide hydrolase (also known as epoxide hydratase) functions in detoxication during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic compounds. Deficiency in this enzyme in patients receiving aromatic-type anti-epileptic drugs such as phenytoin is reported to lead to DRESS syndrome.Epoxides are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are also mutagenic. Epoxide hydrolase is present in large quantity on endoplasmic reticulum.".
Epoxide_hydrolase ecNumber "3.3.2.10".
Epoxide_hydrolase ecNumber "3.3.2.9".
Epoxide_hydrolase thumbnail Epoxide_Hydrolase_B_(2E3J).png?width=300.
Epoxide_hydrolase wikiPageExternalLink www.epoxyde.hydrolase.mahjoubi.com.
Epoxide_hydrolase wikiPageID "1173580".
Epoxide_hydrolase wikiPageRevisionID "591219148".
Epoxide_hydrolase altsymbols "ABHD7".
Epoxide_hydrolase altsymbols "ABHD9".
Epoxide_hydrolase arm "p".
Epoxide_hydrolase arm "q".
Epoxide_hydrolase band "13.13".
Epoxide_hydrolase band "21".
Epoxide_hydrolase band "22.1".
Epoxide_hydrolase band "42.1".
Epoxide_hydrolase caption "Epoxide hydrolase from Mycobacterium tuberculosis.".
Epoxide_hydrolase casNumber "9048".
Epoxide_hydrolase chromosome "1".
Epoxide_hydrolase chromosome "19".
Epoxide_hydrolase chromosome "8".
Epoxide_hydrolase ecNumber "3.3".
Epoxide_hydrolase ecnumber "3.3".
Epoxide_hydrolase entrezgene "2052".
Epoxide_hydrolase entrezgene "2053".
Epoxide_hydrolase entrezgene "253152".
Epoxide_hydrolase entrezgene "79852".
Epoxide_hydrolase goCode "33961".
Epoxide_hydrolase goCode "4301".
Epoxide_hydrolase hasPhotoCollection Epoxide_hydrolase.
Epoxide_hydrolase hgncid "23758".
Epoxide_hydrolase hgncid "23760".
Epoxide_hydrolase hgncid "3401".
Epoxide_hydrolase hgncid "3402".
Epoxide_hydrolase iubmbEcNumber "3".
Epoxide_hydrolase name EPHX1.
Epoxide_hydrolase name "epoxide hydrolase 2, cytoplasmic".
Epoxide_hydrolase name "epoxide hydrolase 3".
Epoxide_hydrolase name "epoxide hydrolase 4".
Epoxide_hydrolase name "microsomal epoxide hydrolase".
Epoxide_hydrolase name "soluble epoxide hydrolase".
Epoxide_hydrolase omim "132810".
Epoxide_hydrolase omim "132811".
Epoxide_hydrolase refseq "NM_000120".
Epoxide_hydrolase refseq "NM_001979".
Epoxide_hydrolase refseq "NM_024794".
Epoxide_hydrolase refseq "NM_173567".
Epoxide_hydrolase symbol EPHX1.
Epoxide_hydrolase symbol "EPHX2".
Epoxide_hydrolase symbol "EPHX3".
Epoxide_hydrolase symbol "EPHX4".
Epoxide_hydrolase uniprot "P34913".
Epoxide_hydrolase uniprot "Q8IUS5".
Epoxide_hydrolase uniprot "Q9H6B9".
Epoxide_hydrolase uniprot "Q9NQV0".
Epoxide_hydrolase subject Category:EC_3.3.
Epoxide_hydrolase subject Category:Metabolism.
Epoxide_hydrolase type Biomolecule.
Epoxide_hydrolase type Enzyme.
Epoxide_hydrolase type ProteinMolecule.
Epoxide_hydrolase type BiologicalObject.
Epoxide_hydrolase comment "Epoxide hydrolase (also known as epoxide hydratase) functions in detoxication during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic compounds.".
Epoxide_hydrolase label "Epoxide hydrolase".
Epoxide_hydrolase sameAs m.04df5m.
Epoxide_hydrolase sameAs Q5383823.
Epoxide_hydrolase sameAs Q5383823.
Epoxide_hydrolase wasDerivedFrom Epoxide_hydrolase?oldid=591219148.
Epoxide_hydrolase depiction Epoxide_Hydrolase_B_(2E3J).png.
Epoxide_hydrolase isPrimaryTopicOf Epoxide_hydrolase.
Epoxide_hydrolase name "microsomal epoxide hydrolase".
Epoxide_hydrolase name "soluble epoxide hydrolase".